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Radiology, Vol 156, 362-362, Copyright © 1985 by Radiological Society of North America

ARTICLES

Hyperimmunoglobulinemia E syndrome: association with osteoporosis and recurrent fractures

SG Kirchner, CJ Sivit and PF Wright

Hyperimmunoglobulinemia E (Job or Buckley) syndrome is an immunodeficiency disease associated with recurrent pyogenic infections, chronic eczematoid dermatitis, and mucocutaneous candidiasis. Association of this condition with osteoporosis and recurrent fractures is presented by a case report and by review of other reports describing similar findings. Other immunodeficiency syndromes with associated skeletal abnormalities are discussed.


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