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Radiology, Vol 156, 741-742, Copyright © 1985 by Radiological Society of North America

ARTICLES

MR effect on murine spermatogenesis

HR Withers, KA Mason and CA Davis

The cytotoxic effects of magnetic resonance (MR) on spermatogenesis in mice were studied. Mice were exposed to a strong static magnetic field from a 0.3-T MR imaging device. The effect of this treatment on different classes of spermatogenic cells was investigated by counting sperm heads at various times after exposure. Sixty-six hours of continuous exposure did not produce any significant cytotoxicity to these cells. This period of continuous exposure is far longer than any anticipated occupational exposure to humans. Thus, acute and subacute exposure to static magnetic fields associated with diagnostic use of MR imaging devices is unlikely to have any significant adverse effect on spermatogenesis.




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