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Radiology, Vol 157, 803-806, Copyright © 1985 by Radiological Society of North America

ARTICLES

Neurofibromas: location by scanning with Tc-99m DTPA. Work in progress

GA Mandell, WC Herrick, HT Harcke, C Sharkey, KM Brooks and GD MacEwen

The accumulation of technetium-99m diethylenetriamine pentaacetic acid (Tc-99m DTPA) in benign soft-tissue neurofibromatosis tumors is reported. In a series of 16 patients with clinical stigmata of neurofibromatosis, 28 sites of abnormal soft-tissue localization of the isotope observed scintigraphically were documented to be sites of soft- tissue tumor by clinical and/or radiographic (predominantly computed tomographic) correlations. The smallest lesion detected was a 1.5-cm subcutaneous neurofibroma. Normal physiologic nonrenal distribution of the Tc-99m DTPA was established by scintigraphic imaging of a control population.




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