Radiology, Vol 162, 151-156, Copyright © 1987 by Radiological Society of North America

ARTICLES

Differential diagnosis of bronchiolitis obliterans with organizing pneumonia and usual interstitial pneumonia: clinical, functional, and radiologic findings

NL Muller, ML Guerry-Force, CA Staples, JL Wright, B Wiggs, C Coppin, P Pare and JC Hogg

To assess the role of chest radiography in the differential diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP) and usual interstitial pneumonia (UIP), records of 34 patients with biopsy-proved BOOP (16 patients) or UIP (18 patients) were reviewed. Chest radiographs taken before biopsy were available in 26 patients, clinical information in 33, and pulmonary function data in 22. These data were reviewed independently, without knowledge of the pathologic diagnosis. The clinical symptoms of BOOP were similar to those of UIP, although the duration of symptoms was longer in UIP (P less than .05), and the prevalence of systemic symptoms was higher in BOOP (P less than .025). The physical findings were similar except that finger clubbing was more common in patients with UIP than in those with BOOP (P less than .01). There was no significant difference in lung volumes, flows, or diffusing capacity between BOOP and UIP. The chest radiograph showed distinguishing features between UIP and BOOP in 23 of 26 patients. The most characteristic radiologic finding in BOOP was the presence of patchy areas of air-space consolidation (eight of 11 patients).

This article has been cited by other articles:

				C. Mueller-Mang, C. Grosse, K. Schmid, L. Stiebellehner, and A. A. Bankier What Every Radiologist Should Know about Idiopathic Interstitial Pneumonias RadioGraphics, May 1, 2007; 27(3): 595 - 615. [Abstract] [Full Text] [PDF]

				J-F. Cordier Cryptogenic organising pneumonia. Eur. Respir. J., August 1, 2006; 28(2): 422 - 446. [Abstract] [Full Text] [PDF]

				D. A. Lynch, W. D. Travis, N. L. Muller, J. R. Galvin, D. M. Hansell, P. A. Grenier, and T. E. King Jr Idiopathic Interstitial Pneumonias: CT Features Radiology, July 1, 2005; 236(1): 10 - 21. [Abstract] [Full Text] [PDF]

				T Fischer, J H Reynolds, and S E Trotter The idiopathic interstitial pneumonias: a beginner's guide Imaging, October 1, 2004; 16(1): 37 - 49. [Abstract] [Full Text] [PDF]

				G. C. Ooi, P. L. Khong, N. L. Muller, W. C. Yiu, L. J. Zhou, J. C. M. Ho, B. Lam, S. Nicolaou, and K. W. T. Tsang Severe Acute Respiratory Syndrome: Temporal Lung Changes at Thin-Section CT in 30 Patients Radiology, March 1, 2004; 230(3): 836 - 844. [Abstract] [Full Text] [PDF]

				J. H. Ryu, J. L. Myers, and S. J. Swensen Bronchiolar Disorders Am. J. Respir. Crit. Care Med., December 1, 2003; 168(11): 1277 - 1292. [Abstract] [Full Text] [PDF]

				T. D. Freudenberger, D. K. Madtes, J. R. Curtis, P. Cummings, B. E. Storer, and R. C. Hackman Association between acute and chronic graft-versus-host disease and bronchiolitis obliterans organizing pneumonia in recipients of hematopoietic stem cell transplants Blood, November 15, 2003; 102(10): 3822 - 3828. [Abstract] [Full Text] [PDF]

				N. Kaminski, J. A. Belperio, P. B. Bitterman, L. Chen, S. W. Chensue, A. M.K. Choi, S. Dacic, J. H. Dauber, R. M. du Bois, J. J. Enghild, et al. Idiopathic Pulmonary Fibrosis Am. J. Respir. Cell Mol. Biol., September 1, 2003; 29(3): S1 - 105. [Full Text] [PDF]

				C. Wittram, E. J. Mark, and T. C. McLoud CT-Histologic Correlation of the ATS/ERS 2002 Classification of Idiopathic Interstitial Pneumonias RadioGraphics, September 1, 2003; 23(5): 1057 - 1071. [Abstract] [Full Text] [PDF]

				American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias . This Joint Statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS Board of Directors, June 2001 and by The ERS Executive Committee, June 2001 Am. J. Respir. Crit. Care Med., January 15, 2002; 165(2): 277 - 304. [Full Text] [PDF]

				G. W. HUNNINGHAKE, M. B. ZIMMERMAN, D. A. SCHWARTZ, T. E. KING JR., J. LYNCH, R. HEGELE, J. WALDRON, T. COLBY, N. MULLER, D. LYNCH, et al. Utility of a Lung Biopsy for the Diagnosis of Idiopathic Pulmonary Fibrosis Am. J. Respir. Crit. Care Med., July 15, 2001; 164(2): 193 - 196. [Abstract] [Full Text] [PDF]

				R. LAZOR, A. VANDEVENNE, A. PELLETIER, P. LECLERC, I. COURT-FORTUNE, and J.-F. CORDIER Cryptogenic Organizing Pneumonia . Characteristics of Relapses in a Series of 48 Patients Am. J. Respir. Crit. Care Med., August 1, 2000; 162(2): 571 - 577. [Abstract] [Full Text] [PDF]

				J.-F. Cordier Rare diseases bullet 8: Organising pneumonia Thorax, April 1, 2000; 55(4): 318 - 328. [Full Text]