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Radiology, Vol 163, 467-470, Copyright © 1987 by Radiological Society of North America

ARTICLES

Light scan evaluation of nonpalpable breast lesions [published erratum appears in Radiology 1987 Oct;165(1):292]

B Monsees, JM Destouet and D Gersell

Transillumination light scanning of the breast was performed immediately before needle localization of 112 nonpalpable mammographic abnormalities detected in 103 patients. Twenty-four cancers were diagnosed in 23 patients. The positive predictive value for mammography was 21%. Ten (42%) of these nonpalpable cancers were not visible on transillumination light scanning. Eleven of 16 invasive ductal cancers and three of seven intraductal cancers were evident on transillumination light scans, but a single case of lobular carcinoma in situ was not evident. There were 12 false-positive light scan examinations. Transillumination light scanning had a 58% sensitivity, an 86% specificity, a 54% positive predictive value, and an 88% negative predictive value for small breast lesions. Therefore, the authors are unable to recommend delaying biopsy in patients with mammographic abnormalities on the basis of a negative light scan study.


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C. Bremer, C.-H. Tung, A. Bogdanov Jr, and R. Weissleder
Imaging of Differential Protease Expression in Breast Cancers for Detection of Aggressive Tumor Phenotypes
Radiology, March 1, 2002; 222(3): 814 - 818.
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