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Radiology, Vol 165, 445-448, Copyright © 1987 by Radiological Society of North America

ARTICLES

Gestational trophoblastic neoplasia: diagnosis with Doppler US

KJ Taylor, PE Schwartz and EI Kohorn
Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, CT 06510.

The sonographic appearance of gestational trophoblastic neoplasia is nonspecific and also seen in complete or partial hydatidiform mole, hydropic degeneration, degenerating fibroids, or ovarian dysgerminomas. Correlation with the serum human chorionic gonadotropin (hCG) level may be helpful since levels exceeding 100,000 IU/L are strongly suggestive of gestational trophoblastic neoplasia. However, low hCG levels may also be found in the presence of this disease. The authors studied six patients who were suspected of having gestational trophoblastic neoplasia. Three of the six proved to have incomplete abortions or molar degeneration. Doppler ultrasound (US) was used to record the signal in the uterine arteries of these patients. The signals were compared with those of three nongravid volunteers and three patients in the first trimester of pregnancy. Analysis of the signals in the uterine artery showed higher systolic and diastolic Doppler shifts in gestational trophoblastic neoplasia when compared with postabortal, gravid, and nongravid signals. These preliminary results indicate that Doppler US has the potential to be clinically useful in the diagnosis of gestational trophoblastic neoplasia.


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 J Ultrasound MedHome page
Q. Zhou, X.-Y. Lei, Q. Xie, and J. D. Cardoza
Sonographic and Doppler Imaging in the Diagnosis and Treatment of Gestational Trophoblastic Disease: A 12-Year Experience
J. Ultrasound Med., January 1, 2005; 24(1): 15 - 24.
[Abstract] [Full Text] [PDF]


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