Radiology, Vol 166, 81-87, Copyright © 1988 by Radiological Society of North America

ARTICLES

Normal and diseased isolated lungs: high-resolution CT

WR Webb, MG Stein, WE Finkbeiner, JG Im, D Lynch and G Gamsu
Department of Radiology, University of California School of Medicine, San Francisco 94143-0628.

High-resolution computed tomography (CT) scans of 12 isolated, inflated, fresh lungs obtained at autopsy were compared with thin, paper-mounted lung sections obtained at the same levels. In six lungs considered intrinsically normal, high-resolution CT showed normal interlobular septa and pulmonary arteries in the lobular core, but lobular bronchioles were not visible. Edematous fluid resulted in thickening and increased visibility of interlobular septa. In three emphysematous lungs, high-resolution CT accurately demonstrated the degree of emphysema and suggested its centrilobular nature. In two lungs with honeycombing, cysts lined by fibrosis were easily seen on high-resolution CT scans. In less severely involved areas, septal thickening and intralobular fibrosis were seen on high-resolution CT scans, but small (1 mm) cysts were invisible. High-resolution CT was able to demonstrate some features of the normal secondary pulmonary lobule and structural alterations produced by various diseases.

This article has been cited by other articles:

				D. M. Hansell, A. A. Bankier, H. MacMahon, T. C. McLoud, N. L. Muller, and J. Remy Fleischner Society: Glossary of Terms for Thoracic Imaging Radiology, March 1, 2008; 246(3): 697 - 722. [Abstract] [Full Text] [PDF]

				W. R. Webb Thin-Section CT of the Secondary Pulmonary Lobule: Anatomy and the Image--The 2004 Fleischner Lecture Radiology, May 1, 2006; 239(2): 322 - 338. [Abstract] [Full Text] [PDF]

				N. A. Sibtain, M. Ujita, R. Wilson, A. U. Wells, and D. M. Hansell Interlobular Septal Thickening in Idiopathic Bronchiectasis: A Thin-Section CT Study of 94 Patients Radiology, December 1, 2005; 237(3): 1091 - 1096. [Abstract] [Full Text] [PDF]

				N L Muller and H Coxson Chronic obstructive pulmonary disease * 4: Imaging the lungs in patients with chronic obstructive pulmonary disease Thorax, November 1, 2002; 57(11): 982 - 985. [Abstract] [Full Text] [PDF]

				T. Johkoh, N. L. Muller, T. V. Colby, K. Ichikado, H. Taniguchi, Y. Kondoh, K. Fujimoto, M. Kinoshita, H. Arakawa, H. Yamada, et al. Nonspecific Interstitial Pneumonia: Correlation between Thin-Section CT Findings and Pathologic Subgroups in 55 Patients Radiology, October 1, 2002; 225(1): 199 - 204. [Abstract] [Full Text] [PDF]

				E. A. Kazerooni High-Resolution CT of the Lungs Am. J. Roentgenol., September 1, 2001; 177(3): 501 - 519. [Full Text] [PDF]

				T. Johkoh, H. Itoh, N. L. Müller, K. Ichikado, H. Nakamura, J. Ikezoe, M. Akira, and T. Nagareda Crazy-paving Appearance at Thin-Section CT: Spectrum of Disease and Pathologic Findings Radiology, April 1, 1999; 211(1): 155 - 160. [Abstract] [Full Text]

				B. W. Levine and V. Nickeleit Case 5-1994- A 34-Year-Old Woman with Mild Exertional Dyspnea and Interstitial Pulmonary Lesions N. Engl. J. Med., February 3, 1994; 330(5): 347 - 353. [Full Text]