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Radiology, Vol 172, 791-792, Copyright © 1989 by Radiological Society of North America

ARTICLES

Cerebral Erdheim-Chester disease: persistent enhancement with Gd-DTPA on MR images

RD Tien, RC Brasch, DE Jackson and WP Dillon
Department of Radiology, University of California San Francisco 94143.

A case of Erdheim-Chester disease with intracerebral masses containing characteristic lipid-laden histiocytes is presented. These unusual lesions remained enhanced on magnetic resonance images obtained 8 days after injection of gadolinium diethylenetriaminepentaacetic acid (DTPA) dimeglumine. Chemical analysis of a biopsy specimen revealed a high concentration of gadolinium. Findings suggest that the Gd-DTPA complex or possibly a gadolinium-containing metabolite may be retained for extended periods in this unusual type of histiocytic lesion.


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