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Radiology, Vol 177, 659-665, Copyright © 1990 by Radiological Society of North America


ARTICLES

Fourier analysis of cerebrospinal fluid flow velocities: MR imaging study. The Scandinavian Flow Group

C Thomsen, F Stahlberg, M Stubgaard and B Nordell
Department of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen, Denmark.

An interleaved pseudocinematographic FLASH (fast low-angle shot) sequence with additional pulsed gradients for flow encoding was used to quantify cerebrospinal fluid (CSF) flow velocities and CSF production. Flow-dependent phase information was obtained by subtracting two differently encoded phase images. The phase information in the resultant image was converted to flow velocity with a calibration curve with the slope 26.5 radian.m-1.sec. The velocity versus time function was Fourier transformed and a continuous curve was fitted to the measured data with use of the first three harmonics. The in vivo measurements showed a significant variation in flow velocities in the cerebral aqueduct (range, 6-51 mm/sec). Calculated CSF production was in the range of 0.6-1.2 L/24 h. The present method gives valuable information about CSF hydrodynamics in an imaging time of less than 8 minutes.


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