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Radiology, Vol 179, 371-376, Copyright © 1991 by Radiological Society of North America

ARTICLES

Dynamic gadolinium-enhanced rapid acquisition spin-echo MR imaging of the liver

SA Mirowitz, JK Lee, E Gutierrez, JJ Brown, JP Heiken and SS Eilenberg
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.

Rapid acquisition spin-echo (RASE) magnetic resonance (MR) imaging allows for coverage of the entire liver with highly T1-weighted SE images during a single 23-second breath-holding period. The RASE sequence was implemented in conjunction with rapid intravenous injection of gadopentetate dimeglumine to enable performance of dynamic contrast material-enhanced MR imaging of the liver. Prospective evaluation of 24 patients with 62 liver lesions 1 cm or greater in diameter was performed. Images obtained with RASE were devoid of respiratory-related ghost artifacts or edge blurring. The dynamic contrast-enhanced RASE technique resulted in contrast-to-noise and contrast-to-artifact values and time efficiency measures significantly greater (P less than .05) than those obtained with use of conventional T1- and T2-weighted pulse sequences, indicating a higher likelihood for lesion detectability. Lesion conspicuity was maximal during or immediately following bolus administration of gadopentetate dimeglumine, with lesions often becoming obscured at delayed postcontrast imaging.


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