Radiology, Vol 180, 707-710, Copyright © 1991 by Radiological Society of North America

ARTICLES

Extravasation of iopamidol and iohexol during contrast-enhanced CT: report of 28 cases

CL Sistrom, SB Gay and L Peffley
Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908.

Extravasation of intravenously injected contrast medium is a well-known complication of radiologic procedures. Records from a 27-month period were reviewed of 28 patients in whom extravasation of nonionic contrast medium occurred during computed tomographic (CT) scanning. Extravasated amounts ranged from 3 mL in an infant to 100 mL in an adult. There were seven documented major (50-100-mL) events and nine documented moderate (10-49-mL) events. Follow-up showed that none of these patients required medical or surgical intervention as a result of extravasation. The rate of extravasation during neurologic CT scanning (head, orbits, and spine) was 0.09%, while the rate for the rest of the body (chest, abdomen, pelvis, neck) was 0.17%; the overall rate was 0.14%. The higher rate for non-neurologic studies was related to the use of a power injector. Nonionic contrast medium seemed to cause fewer systemic reactions.

This article has been cited by other articles:

				J. C. Weinreb Which Study When? Is Gadolinium-enhanced MR Imaging Safer than Iodine-enhanced CT? Radiology, October 1, 2008; 249(1): 3 - 8. [Full Text] [PDF]

				C. L. Wang, R. H. Cohan, J. H. Ellis, S. Adusumilli, and N. R. Dunnick Frequency, Management, and Outcome of Extravasation of Nonionic Iodinated Contrast Medium in 69 657 Intravenous Injections Radiology, April 1, 2007; 243(1): 80 - 87. [Abstract] [Full Text] [PDF]

				J. G. Amaral, J. Traubici, G. BenDavid, G. Reintamm, and A. Daneman Safety of power injector use in children as measured by incidence of extravasation. Am. J. Roentgenol., August 1, 2006; 187(2): 580 - 583. [Abstract] [Full Text] [PDF]

				P. C. Sanelli, M. Deshmukh, I. Ougorets, R. Caiati, and L. A. Heier Safety and Feasibility of Using a Central Venous Catheter for Rapid Contrast Injection Rates Am. J. Roentgenol., December 1, 2004; 183(6): 1829 - 1834. [Abstract] [Full Text] [PDF]

				B. R. Herts, C. M. O'Malley, S. L. Wirth, M. L. Lieber, and B. Pohlman Power Injection of Contrast Media Using Central Venous Catheters: Feasibility, Safety, and Efficacy Am. J. Roentgenol., February 1, 2001; 176(2): 447 - 453. [Abstract] [Full Text] [PDF]

				C. C. Powell, J. m. Li, L. Rodino, and F. A. Anderson A New Device to Limit Extravasation During Contrast-Enhanced CT Am. J. Roentgenol., February 1, 2000; 174(2): 315 - 318. [Abstract] [Full Text] [PDF]

				B. A. Birnbaum, R. C. Nelson, J. L. Chezmar, and S. N. Glick Extravasation Detection Accessory: Clinical Evaluation in 500 Patients Radiology, August 1, 1999; 212(2): 431 - 438. [Abstract] [Full Text]