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Radiology, Vol 186, 273-278, Copyright © 1993 by Radiological Society of North America

ARTICLES

Cutaneous T-cell lymphoma: CT in evaluation and staging

JC Bass, MT Korobkin, KD Cooper, NM Kane and JF Platt
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0030.

Among 63 patients with cutaneous T-cell lymphoma (CTCL), 29% (n = 18) had positive computed tomographic (CT) findings, with frequencies of 65% (n = 13) among patients thought to have stages II-IV disease at clinical examination and 12% (n = 5) among patients thought to have stage I. Among eight patients with atypical CTCL variants such as cutaneous large-cell lymphoma, only one had negative findings at CT; extracutaneous disease was not suspected in five before they underwent CT. In contrast, CT findings were positive in only 5% (n = 2) of patients with classic early mycosis fungoides-type CTCL (scaling patches, small epidermotropic CD4+ cells), and CT is unlikely to provide substantial information in this patient subgroup. Contrary to earlier reports, the authors' data suggest that body CT is extremely useful in staging and evaluating patients with CTCL. CT should be included in the evaluation of atypical CTCL variants, Sezary syndrome, advanced-stage mycosis fungoides, and cases in which the CTCL subtype is unclear.


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