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Radiology, Vol 186, 467-469, Copyright © 1993 by Radiological Society of North America

ARTICLES

Regional variations in bone mineral density as assessed with dual- energy photon absorptiometry and dual x-ray absorptiometry

AJ Feyerabend and JL Lear
Department of Radiology, University of Colorado Health Sciences Center, Denver 80262.

Total-body, lumbar spine, and hip bone mineral density (BMD) scans were obtained in postmenopausal women to examine regional variations in mineralization of trabecular bone. One hundred ninety-nine patients were studied with dual-energy photon absorptiometry (DPA) and/or dual x- ray absorptiometry (DXA). Comparison of BMD at the different sites showed statistically significant correlations (P < .001) among all the sites; however, variations between sites were observed in many patients. Total-body measurements were within normal limits as defined by the system software in 90% of patients with substantial bone mineral loss in the spine or hip. Lumbar spine measurements calculated from the total-body scan differed from the direct measurements by an average of 10% (DPA) and 12% (DXA). These results suggest that site-specific measurements are required to assess regional osteopenia. While total- body scans may be precise and offer the advantage of total-body composition determination, BMD values derived from total-body scans cannot currently replace direct measurements.


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M BOYANOV
Estimation of lumbar spine bone mineral density by dual-energy X-ray absorptiometry: standard anteroposterior scans vs sub-regional analyses of whole-body scans
Br. J. Radiol., August 1, 2008; 81(968): 637 - 642.
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