Radiology, Vol 186, 515-522, Copyright © 1993 by Radiological Society of North America

ARTICLES

Coaxial percutaneous biopsy technique with automated biopsy devices: value in improving accuracy and negative predictive value

JS Moulton and PT Moore
Department of Radiology, St Anthony Hospital, Denver, CO 80204.

Three hundred percutaneous biopsies were performed in 267 consecutive patients by means of a coaxial technique with use of 18- and 20-gauge automated cutting biopsy devices and 22-gauge aspiration needles. Thoracic, hepatic, renal, pancreatic, adrenal, splenic, retroperitoneal, and musculoskeletal soft-tissue masses were sampled. For malignant masses (229 cases), the sensitivity was 79% for cytologic analysis, 88% for histologic analysis, and 92% for both combined. In benign disease (71 cases), a correct specific diagnosis was made with cytologic analysis in 38%, with histologic analysis in 97%, and with both combined in 97%. The negative predictive value was 60% for cytologic analysis, 72% for histologic analysis, and 80% for both combined. When only cancer-negative results in which a specific benign diagnosis was made were considered, the negative predictive value was 100% for cytologic analysis, 97% for histologic analysis, and 97% for both combined. The positive predictive value was 100% for both cytologic and histologic analysis. Bleeding complications occurred in 3% of biopsies, including in one patient who died.

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