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Radiology, Vol 188, 283-285, Copyright © 1993 by Radiological Society of North America

ARTICLES

Malignant hepatic tumors: safety of high-dose percutaneous ethanol ablation therapy

RD Redvanly, JL Chezmar, RM Strauss, JR Galloway, TD Boyer and ME Bernardino
Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322.

The authors retrospectively analyzed clinical records to determine the safety and complication rate of percutaneous ethanol ablation therapy with more than 10 mL of ethanol administered per session for treatment of malignant hepatic tumors. Ten patients underwent a total of 35 sessions with 10 mL or more of ethanol, and four underwent 18 sessions with 10 mL or less. No serious complications occurred with any dose. Pain and fever were the most common complications at all doses, and the higher frequency of these at larger ethanol volumes may be related to the greater degree of tumor necrosis induced by the larger volume.


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