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Radiology, Vol 190, 417-423, Copyright © 1994 by Radiological Society of North America
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B Hamm, RF Thoeni, RG Gould, ME Bernardino, M Luning, S Saini, AE Mahfouz, M Taupitz and KJ Wolf
Department of Radiology, Steglitz Clinic, Freie Universitat Berlin, Germany.
PURPOSE: To evaluate prospectively the diagnostic accuracy of non- enhanced and gadolinium-enhanced magnetic resonance (MR) imaging in characterization of hepatic lesions. MATERIALS AND METHODS: Fifty-five patients with benign and 52 patients with malignant focal liver lesions underwent examination at 1.5 T that comprised nonenhanced and dynamic contrast material-enhanced images. Four experienced radiologists independently read the different sets of images without and with knowledge of clinical history. RESULTS: Receiver operating characteristic analysis showed that dynamic contrast-enhanced MR imaging added information to nonenhanced MR studies and thereby improved distinction between benign and malignant lesions (P < .05). Knowledge of clinical data further improved lesion characterization with nonenhanced and combined nonenhanced and contrast-enhanced MR imaging (P < .05). CONCLUSION: Dynamic contrast-enhanced MR imaging is a useful adjunct for characterization of hepatic lesions. Knowledge of clinical history still has a decisive effect on interpretation of MR images of the liver.
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