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Radiology, Vol 191, 539-543, Copyright © 1994 by Radiological Society of North America

ARTICLES

Infectious liver foci in leukemia: comparison of short-inversion-time inversion-recovery, T1-weighted spin-echo, and dynamic gadolinium- enhanced MR imaging

AE Lamminen, VJ Anttila, S Bondestam, T Ruutu and PJ Ruutu
Department of Radiology, Helsinki University Hospital, Finland.

PURPOSE: To assess the performances of three different magnetic resonance (MR) imaging techniques in the evaluation of patients with leukemia and suspected hepatic candidiasis. MATERIALS AND METHODS: Twelve patients with acute leukemia and definite or clinically suspected hepatic candidiasis were imaged at 1.0 T with a T1-weighted spin-echo (SE) technique, a short-inversion-time inversion-recovery (STIR) fat-suppression technique, and a dynamic gadolinium-enhanced fast low-angle shot (FLASH) technique. The conspicuity of hepatic lesions was evaluated semiquantitatively and ranked on a three-point scale. RESULTS: Multiple liver lesions were seen as high-signal- intensity foci with the STIR sequence; other sequences showed equivocal results. In the semiquantitative evaluation, STIR was significantly (P < .001) superior to both T1-weighted SE and contrast-enhanced FLASH techniques. Multiple red blood cell transfusions affected lesion conspicuity. CONCLUSION: STIR imaging is recommended as the MR technique of choice at 1.0 T in the evaluation of infectious liver foci in patients with acute leukemia.


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