Radiology, Vol 192, 47-54, Copyright © 1994 by Radiological Society of North America

ARTICLES

Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project comparison of three MR imaging techniques

CM Tempany, X Zhou, EA Zerhouni, MD Rifkin, LE Quint, CW Piccoli, JH Ellis and BJ McNeil
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, Md.

PURPOSE: To assess accuracy of three different magnetic resonance (MR) imaging techniques, including the endorectal coil, in staging prostate cancer. MATERIALS AND METHODS: MR imaging was performed in 213 patients with prostate cancer with a conventional body coil, with fat suppression and a body coil, and with an endorectal coil. Radiologists identified tumor invasion into periprostatic tissues, neurovascular bundles, and seminal vesicles. Each technique was evaluated separately, and in a subset of 74 patients the three techniques were evaluated together. Images obtained with the two body-coil techniques were read in combination with images obtained with the endorectal coil (combination A) and alone (combination B). RESULTS: Overall accuracy for conventional body-coil, fat-suppressed body-coil, and endorectal- coil MR was 61%, 64%, and 54%, respectively. Overall group accuracy for combinations A and B was 57% and 61%. Considerable interreader variability was found for combination A. CONCLUSION: No technique was highly accurate for staging early prostate cancer. Individual radiologists did achieve a high degree of staging accuracy with the endorectal-coil and body-coil combination.

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