Radiology, Vol 192, 759-764, Copyright © 1994 by Radiological Society of North America

ARTICLES

Isolated mild fetal cerebral ventriculomegaly: clinical course and outcome

MD Patel, AL Filly, DR Hersh and RB Goldstein
Department of Radiology, University of California, San Francisco.

PURPOSE: To assess the outcome of fetuses with isolated mild ventriculomegaly (IMVM). MATERIALS AND METHODS: The clinical course of 44 fetuses with IMVM was investigated. Cognitive and motor development was classified as normal or delayed. RESULTS: Clinical data were available for 37 subjects. Three (8%) neonates died. Of the 34 living children, follow-up was limited (< 9 months) in six and the clinical course beyond the 1st year of life was established in 28. Twenty-two (79%) of the 28 children are developing normally, whereas six (21%) are developmentally delayed. More than 90% of fetuses with ventricular atrial diameter of 10-11 mm are normal. Seventy-five percent of fetuses with IMVM were male. With exclusion of the six children with limited follow-up, 78% of boys older than 1 year are developmentally normal compared with only 50% of girls. CONCLUSION: The majority of living children with prenatally detected IMVM are developmentally normal, especially those with borderline ventriculomegaly. Gender differences in prevalence and outcome deserve further investigation.

This article has been cited by other articles:

				J. F. Kazan-Tannus, V. Dialani, M. L. Kataoka, G. Chiang, H. A. Feldman, J. S. Brown, and D. Levine MR Volumetry of Brain and CSF in Fetuses Referred for Ventriculomegaly Am. J. Roentgenol., July 1, 2007; 189(1): 145 - 151. [Abstract] [Full Text] [PDF]

				O.A. Glenn and A.J. Barkovich Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1. AJNR Am. J. Neuroradiol., September 1, 2006; 27(8): 1604 - 1611. [Abstract] [Full Text] [PDF]

				F. V. Coakley, O. A. Glenn, A. Qayyum, A. J. Barkovich, R. Goldstein, and R. A. Filly Fetal MRI: A Developing Technique for the Developing Patient Am. J. Roentgenol., January 1, 2004; 182(1): 243 - 252. [Full Text] [PDF]

				M Wyldes and M Watkinson Isolated mild fetal ventriculomegaly Arch. Dis. Child. Fetal Neonatal Ed., January 1, 2004; 89(1): F9 - F13. [Abstract] [Full Text] [PDF]

				P CHUMAS, A TYAGI, and J LIVINGSTON Hydrocephalus---what's new? Arch. Dis. Child. Fetal Neonatal Ed., November 1, 2001; 85(3): F149 - 154. [Full Text] [PDF]

				E. M. Simon, R. B. Goldstein, F. V. Coakley, R. A. Filly, K. C. Broderick, T. J. Musci, and A. J. Barkovich Fast MR Imaging of Fetal CNS Anomalies in Utero AJNR Am. J. Neuroradiol., October 1, 2000; 21(9): 1688 - 1698. [Abstract] [Full Text]

				P. J. Santosh Current topic: Neuroimaging in child and adolescent psychiatric disorders Arch. Dis. Child., May 1, 2000; 82(5): 412 - 419. [Abstract] [Full Text]

				D. LEVINE, P. D. BARNES, J. R. MADSEN, J. ABBOTT, T. MEHTA, and R. R. EDELMAN Central Nervous System Abnormalities Assessed With Prenatal Magnetic Resonance Imaging Obstet. Gynecol., December 1, 1999; 94(6): 1011 - 1019. [Abstract] [Full Text] [PDF]

				D. Levine, P. D. Barnes, and R. R. Edelman Obstetric MR Imaging Radiology, June 1, 1999; 211(3): 609 - 617. [Abstract] [Full Text]

				D. Levine and P. D. Barnes Cortical Maturation in Normal and Abnormal Fetuses as Assessed with Prenatal MR Imaging Radiology, March 1, 1999; 210(3): 751 - 758. [Abstract] [Full Text]