Radiology, Vol 193, 333-339, Copyright © 1994 by Radiological Society of North America

ARTICLES

Prostate carcinoma: assessment of diagnostic criteria for capsular penetration on endorectal coil MR images

EK Outwater, RO Petersen, ES Siegelman, LG Gomella, CE Chernesky and DG Mitchell
Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107-5244.

PURPOSE: To assess the accuracy of using several criteria to evaluate endorectal coil magnetic resonance (MR) images for penetration of the prostatic capsule. MATERIALS AND METHODS: Thirty patients with prostate carcinoma underwent MR imaging and prostatectomy. Specified sites of potential capsular penetration on MR images were blindly evaluated by three readers for six diagnostic criteria. These evaluations were compared with pathologic findings of capsular penetration and were analyzed by means of receiver operating characteristic (ROC) analysis. RESULTS: The area under the ROC curve (Az) for the readers' overall impression of capsular penetration varied from .72 to .77. Highest mean Az's were for the criteria of capsular thickening (.74) and nodular extracapsular tumor (.72), although the latter finding had poor sensitivity (15%). Interobserver variation was low for all findings. CONCLUSION: Sensitivity and specificity were generally low for the diagnostic criteria. The usefulness of endorectal coil MR imaging in staging prostate cancer may be limited by the lack of diagnostic signs that uniformly identify extracapsular penetration.

This article has been cited by other articles:

				H. Hricak, P. L. Choyke, S. C. Eberhardt, S. A. Leibel, and P. T. Scardino Imaging Prostate Cancer: A Multidisciplinary Perspective Radiology, April 1, 2007; 243(1): 28 - 53. [Abstract] [Full Text] [PDF]

				H. Li, K. Sugimura, Y. Kaji, Y. Kitamura, M. Fujii, I. Hara, and M. Tachibana Conventional MRI capabilities in the diagnosis of prostate cancer in the transition zone. Am. J. Roentgenol., March 1, 2006; 186(3): 729 - 742. [Abstract] [Full Text] [PDF]

				J. J. Futterer, S. W. T. P. J. Heijmink, T. W. J. Scheenen, G. J. Jager, C. A. Hulsbergen-Van de Kaa, J. A. Witjes, and J. O. Barentsz Prostate Cancer: Local Staging at 3-T Endorectal MR Imaging--Early Experience Radiology, December 1, 2005; 238(1): 184 - 191. [Abstract] [Full Text] [PDF]

				J. J. Futterer, M. R. Engelbrecht, H. J. Huisman, G. J. Jager, C. A. Hulsbergen-van De Kaa, J. A. Witjes, and J. O. Barentsz Staging Prostate Cancer with Dynamic Contrast-enhanced Endorectal MR Imaging prior to Radical Prostatectomy: Experienced versus Less Experienced Readers Radiology, November 1, 2005; 237(2): 541 - 549. [Abstract] [Full Text] [PDF]

				D. Beyersdorff, K. Taymoorian, T. Knosel, D. Schnorr, R. Felix, B. Hamm, and H. Bruhn MRI of Prostate Cancer at 1.5 and 3.0 T: Comparison of Image Quality in Tumor Detection and Staging Am. J. Roentgenol., November 1, 2005; 185(5): 1214 - 1220. [Abstract] [Full Text] [PDF]

				H Hricak MR imaging and MR spectroscopic imaging in the pre-treatment evaluation of prostate cancer Br. J. Radiol., October 1, 2005; 78(Special_Issue_2): S103 - S111. [Abstract] [Full Text] [PDF]

				A. Qayyum, F. V. Coakley, Y. Lu, J. D. Olpin, L. Wu, B. M. Yeh, P. R. Carroll, and J. Kurhanewicz Organ-Confined Prostate Cancer: Effect of Prior Transrectal Biopsy on Endorectal MRI and MR Spectroscopic Imaging Am. J. Roentgenol., October 1, 2004; 183(4): 1079 - 1083. [Abstract] [Full Text] [PDF]

				F. Cornud, T. Flam, L. Chauveinc, K. Hamida, Y. Chretien, A. Vieillefond, O. Helenon, and J. F. Moreau Extraprostatic Spread of Clinically Localized Prostate Cancer: Factors Predictive of pT3 Tumor and of Positive Endorectal MR Imaging Examination Results Radiology, July 1, 2002; 224(1): 203 - 210. [Abstract] [Full Text]

				A. R. Padhani, A. D. MacVicar, C. J. Gapinski, D. P. Dearnaley, G. J. M. Parker, J. Suckling, M. O. Leach, and J. E. Husband Effects of Androgen Deprivation on Prostatic Morphology and Vascular Permeability Evaluated with MR Imaging Radiology, February 1, 2001; 218(2): 365 - 374. [Abstract] [Full Text]

				F. Cornud, K. Hamida, T. Flam, O. Helenon, Y. Chretien, N. Thiounn, J. M. Correas, J. M. Casanova, and J. F. Moreau Endorectal Color Doppler Sonography and Endorectal MR Imaging Features of Nonpalpable Prostate Cancer: Correlation with Radical Prostatectomy Findings Am. J. Roentgenol., October 1, 2000; 175(4): 1161 - 1168. [Abstract] [Full Text] [PDF]

				J. Scheidler, H. Hricak, D. B. Vigneron, K. K. Yu, D. L. Sokolov, L. R. Huang, C. J. Zaloudek, S. J. Nelson, P. R. Carroll, and J. Kurhanewicz Prostate Cancer: Localization with Three-dimensional Proton MR Spectroscopic Imaging-Clinicopathologic Study Radiology, November 1, 1999; 213(2): 473 - 480. [Abstract] [Full Text]

				K. K. Yu, J. Scheidler, H. Hricak, D. B. Vigneron, C. J. Zaloudek, R. G. Males, S. J. Nelson, P. R. Carroll, and J. Kurhanewicz Prostate Cancer: Prediction of Extracapsular Extension with Endorectal MR Imaging and Three-dimensional Proton MR Spectroscopic Imaging Radiology, November 1, 1999; 213(2): 481 - 488. [Abstract] [Full Text]