Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bizzi, A.
Right arrow Articles by Di Chiro, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bizzi, A.
Right arrow Articles by Di Chiro, G.

Radiology, Vol 194, 271-276, Copyright © 1995 by Radiological Society of North America

ARTICLES

Response of non-Hodgkin lymphoma to radiation therapy: early and long- term assessment with H-1 MR spectroscopic imaging

A Bizzi, B Movsas, G Tedeschi, CL Phillips, P Okunieff, JR Alger and G Di Chiro
Neuroimaging Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892.

PURPOSE: To determine whether proton magnetic resonance (MR) spectroscopic imaging is a sensitive technique for defining tumor extent and assessing response of cerebral lymphoma to therapy. MATERIALS AND METHODS: Four hydrogen-1 MR spectroscopic imaging studies were performed in a patient with non-Hodgkin lymphoma (NHL) before, during, and after radiation therapy and at follow-up at 33 months after diagnosis of the recurrence of disease. The patient had a single, large lesion in the brain and underwent hyperfractionated radiation therapy for 4 weeks. A series of MR images was also obtained. RESULTS: The pretreatment study showed a lesion with a distinct spectral pattern: marked elevation of choline and lipids and great reduction of creatine and N-acetylaspartate. During and after treatment, H-1 MR spectroscopic images depicted a progressive reduction of the abnormal choline and lipid signals. Thirty-three months after treatment, multiple-section H- 1 MR spectroscopic images showed normal spectral patterns in all sections examined. CONCLUSION: H-1 MR spectroscopy may contribute to the neuroradiologic evaluation of NHL and, in particular, may be useful in monitoring therapeutic response.


This article has been cited by other articles:


Home page
 RadiologyHome page
C.-Y. Chen, C.-W. Li, Y.-T. Kuo, T.-S. Jaw, D.-K. Wu, J.-C. Jao, J.-S. Hsu, and G.-C. Liu
Early Response of Hepatocellular Carcinoma to Transcatheter Arterial Chemoembolization: Choline Levels and MR Diffusion Constants--Initial Experience
Radiology, May 1, 2006; 239(2): 448 - 456.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
P. E. Ricci, A. Pitt, P. J. Keller, S. W. Coons, and J. E. Heiserman
Effect of Voxel Position on Single-Voxel MR Spectroscopy Findings
AJNR Am. J. Neuroradiol., February 1, 2000; 21(2): 367 - 374.
[Abstract] [Full Text]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
I L Simone, F Federico, C Tortorella, C F Andreula, G B Zimatore, P Giannini, G Angarano, V Lucivero, P Picciola, D Carrara, et al.
Localised 1H-MR spectroscopy for metabolic characterisation of diffuse and focal brain lesions in patients infected with HIV
J. Neurol. Neurosurg. Psychiatry, April 1, 1998; 64(4): 516 - 523.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1995 by the Radiological Society of North America.