Radiology, Vol 194, 407-412, Copyright © 1995 by Radiological Society of North America

ARTICLES

Clinical evaluation of pulmonary nodules with single-exposure dual- energy subtraction chest radiography with an iterative noise-reduction algorithm

S Kido, J Ikezoe, H Naito, J Arisawa, S Tamura, T Kozuka, W Ito, K Shimura and H Kato
Department of Radiology, Osaka University Medical School, Japan.

PURPOSE: To compare the clinical usefulness of the single-exposure dual- energy subtraction method with an iterative noise-reduction algorithm. MATERIALS AND METHODS: Fourteen radiologists read three sets of images from 44 patients: original computed radiographic images only, original computed radiographic images plus conventional bone-subtracted images, and original computed radiographic images plus iterative noise-reduced bone-subtracted images. Twenty-two patients had one or more (maximum, five) pulmonary nodules; 22 had no pulmonary nodules. Observer performance was evaluated by means of calculation of the average area under the alternative free-response receiver operating characteristic curves (A1). RESULTS: Compared with the original computed radiographic image only, detection of nodules was significantly better with both the original computed radiographic image plus iterative bone-subtracted image (A1 = 0.72 +/- 0.02 and 0.66 +/- 0.02, respectively; P = .01) and the original computed radiographic image plus conventional bone- subtracted image (A1 = 0.66 +/- 0.02 and 0.61 +/- 0.01, respectively; P = .03). CONCLUSION: The iterative noise-reduction algorithm is superior to conventional methods in detection of pulmonary nodules.

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