Radiology, Vol 195, 53-57, Copyright © 1995 by Radiological Society of North America

ARTICLES

Cerebral blood flow: measurement with xenon-enhanced dynamic helical CT

K Nambu, R Suzuki and K Hirakawa
Medical Systems Engineering Department II, Toshiba Corporation, Tochigi, Japan.

PURPOSE: To improve CT number reproducibility in helical CT, a newly developed controlled-orbit helical scan mechanism was applied. The authors developed a method for volumetric measurement of cerebral blood flow (CBF) with dynamic helical computed tomography (CT) after inhalation of xenon gas. MATERIALS AND METHODS: In three subjects (two healthy men aged 22 and 38 years and a 7-year-old girl with moyamoya disease), six helical scans were obtained during 6-minute xenon inhalation, and CT scans with 41 sections in 2-mm increments were reconstructed from each scan. Conventional CBF calculation was then applied to the CT images. RESULTS: CBF maps of 40 sections for each subject of sufficient diagnostic quality were obtained with a 39-cGy radiation dose. The spatial resolution was 2.5 line pairs per centimeter. CONCLUSION: This volumetric CBF mapping method is applicable in clinical practice because of the short examination time and acceptable radiation dose.

This article has been cited by other articles:

				N. Miyazawa, M. Uchida, A. Fukamachi, I. Fukasawa, H. Sasaki, and H. Nukui Xenon Contrast-Enhanced CT Imaging of Supratentorial Hypoperfusion in Patients with Brain Stem Infarction AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1858 - 1862. [Abstract] [Full Text]

				J. L. Sunshine, R. W. Tarr, C. F. Lanzieri, D. M. D. Landis, W. R. Selman, and J. S. Lewin Hyperacute Stroke: Ultrafast MR Imaging to Triage Patients prior to Therapy Radiology, August 1, 1999; 212(2): 325 - 332. [Abstract] [Full Text]