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Radiology, Vol 195, 545-552, Copyright © 1995 by Radiological Society of North America


ARTICLES

AIDS-related Kaposi sarcoma of the lung: radiographic findings and staging system with bronchoscopic correlation

JF Gruden, L Huang, WR Webb, G Gamsu, PC Hopewell and DM Sides
Department of Radiology, San Francisco General Hospital, CA 94110, USA.

PURPOSE: To determine the chest radiographic findings in patients with tracheobronchial Kaposi sarcoma (KS) and to develop a radiographic staging system that allows comparison of radiographic to bronchoscopic findings and allows assessment of the typical temporal progression of pulmonary KS. MATERIALS AND METHODS: The chest radiographs and medical records of 76 male patients, aged 23-60 years (mean, 36 years 4 months) with bronchoscopically proved KS were retrospectively reviewed. Tumor extent at bronchoscopy (grade 1-3) was compared with severity of parenchymal disease (radiographic stage 0-3). RESULTS: There was a statistically significant relationship between extent of tracheobronchial disease and radiographic stage (P = .01). However, in some patients, parenchymal KS of advanced stage was present with no visible endobronchial disease. CONCLUSION: The proposed staging system describes features of early, moderate, and advanced KS. Although there is a correlation between tracheobronchial and parenchymal disease, the latter can occur in the absence of endobronchial lesions.


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