Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Belle, V.
Right arrow Articles by Segebarth, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Belle, V.
Right arrow Articles by Segebarth, C.

Radiology, Vol 195, 739-746, Copyright © 1995 by Radiological Society of North America

ARTICLES

Intracranial gradient-echo and spin-echo functional MR angiography in humans

V Belle, C Delon-Martin, R Massarelli, J Decety, JF Le Bas, AL Benabid and C Segebarth
INSERM U.318/Groupe d'Application de la RMN a la Neurobiologie, Universitaire de Grenoble, France.

PURPOSE: To investigate the predominance of venous signal intensity at 1.5-T gradient-echo (GRE) functional magnetic resonance (MR) imaging of motor activity and to demonstrate the contribution from task-induced changes in flow velocity to the functional MR imaging signal intensity. MATERIALS AND METHODS: Functional MR imaging of motor activity was performed in healthy volunteers. In a first examination, conventional two-dimensional GRE blood oxygenation level-dependent (BOLD) functional MR imaging techniques were used, and the image planes were carefully positioned with respect to the veins that responded to the motor task. In a second examination, two-dimensional spin-echo (SE) techniques were used, and the image planes were oriented axially and measured in a sequential multisection manner. The areas of hyperintensity on functional MR images were eventually processed by means of maximum intensity projection. RESULTS: Functional MR angiograms were obtained in both examinations. The possibility to generate SE functional MR angiograms demonstrates that venous inflow effects may contribute substantially to signal intensity in conventional two-dimensional GRE BOLD functional MR imaging of motor activity. CONCLUSION: Veins have a substantial role in BOLD functional MR imaging of motor activity.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1995 by the Radiological Society of North America.