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Radiology, Vol 196, 115-122, Copyright © 1995 by Radiological Society of North America

ARTICLES

Staging of suspected breast cancer: effect of MR imaging and MR-guided biopsy

SG Orel, MD Schnall, CM Powell, MG Hochman, LJ Solin, BL Fowble, MH Torosian and EF Rosato
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.

PURPOSE: To investigate the effect of contrast material-enhanced magnetic resonance (MR) imaging on staging of breast cancer in patients with mammographically or clinically suspected tumor. MATERIALS AND METHODS: One hundred seventy-six patients underwent breast MR imaging at 1.5 T before excisional biopsy of a suspicious mammographic or palpable abnormality. Diagnostic imaging studies in patients with biopsy-proved or presumed breast carcinoma were reviewed. RESULTS: Sixty-four patients met the study criteria. MR imaging enabled detection of all 57 invasive breast cancers and nine of 15 in situ cancers. In 22 patients (34%), MR imaging depicted one or more cancers not visible at mammography, 13 (20%) of which were unsuspected multifocal or diffuse disease. As a result of the increased sensitivity of MR imaging compared with that of mammography, clinical staging and subsequent treatment were altered in seven patients (11%). CONCLUSION: MR imaging allows detection of mammographically and clinically occult foci of carcinoma in patients with suspected breast cancer.


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