Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wehrli, F. W.
Right arrow Articles by Haddad, J. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wehrli, F. W.
Right arrow Articles by Haddad, J. G.

Radiology, Vol 196, 631-641, Copyright © 1995 by Radiological Society of North America

ARTICLES

Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis

FW Wehrli, JC Ford and JG Haddad
Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.

PURPOSE: To determine if the magnetic resonance (MR) imaging effective transverse relaxation rate (R2*) of trabecular bone marrow is lowered in osteoporosis. MATERIALS AND METHODS: R2* was measured in 146 women. Control subjects (n = 77; mean age, 46.6 years) had high mean spinal bone mineral densities (BMDs) and no vertebral deformities. Patients with spinal osteoporosis (n = 59; mean age, 59.7 years) had at least one thoracic vertebral deformity and/or low BMDs. RESULTS: R2* was lower in patients for L-2 through L-5 (P < .001). Average R2* of L-3 through L-5 (R2*av) was the best discriminator (64.79 sec-1 +/- 1.18 [standard error] for control subjects vs 53.39 sec-1 +/- 1.24 for patients; P < .0001). R2*av decreased with age in control subjects. The difference in R2*av in a subset of 38 age-matched pairs of patients and control subjects was 8.25 sec-1 (P < .0001). Subjects with deformities had lower 52*av than did control subjects (52.3 sec-1 +/- 1.6 vs 62.5 sec-1 +/- 1.1, P < .0001). R2*av was correlated with mean BMD (r = .54, P < .0001). CONCLUSION: Patients with osteoporosis have lower R2*s in vertebral marrow.


This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
J. M. Mathis, J. D. Barr, S. M. Belkoff, M. S. Barr, M. E. Jensen, and H. Deramond
Percutaneous Vertebroplasty: A Developing Standard of Care for Vertebral Compression Fractures
AJNR Am. J. Neuroradiol., February 1, 2001; 22(2): 373 - 381.
[Full Text] [PDF]

Home page
 RadiologyHome page
T. M. Link, A. Lotter, F. Beyer, S. Christiansen, D. Newitt, Y. Lu, C. Schmid, and S. Majumdar
Changes in Calcaneal Trabecular Bone Structure after Heart Transplantation: An MR Imaging Study
Radiology, December 1, 2000; 217(3): 855 - 862.
[Abstract] [Full Text]

Home page
 RadiologyHome page
F. W. Wehrli, J. A. Hopkins, S. N. Hwang, H. K. Song, P. J. Snyder, and J. G. Haddad
Cross-sectional Study of Osteopenia with Quantitative MR Imaging and Bone Densitometry
Radiology, November 1, 2000; 217(2): 527 - 538.
[Abstract] [Full Text]

Home page
 RadiologyHome page
D. Schellinger, C. S. Lin, D. Fertikh, J. S. Lee, W. C. Lauerman, F. Henderson, and B. Davis
Normal Lumbar Vertebrae: Anatomic, Age, and Sex Variance in Subjects at Proton MR Spectroscopy-Initial Experience
Radiology, June 1, 2000; 215(3): 910 - 916.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1995 by the Radiological Society of North America.