Radiology, Vol 198, 819-823, Copyright © 1996 by Radiological Society of North America

ARTICLES

Regional metastasis in head and neck squamous cell carcinoma: revised value of US with US-guided FNAB [published erratum appears in Radiology 1997 Jan;202(1):285]

RP Takes, P Knegt, JJ Manni, CA Meeuwis, HA Marres, HA Spoelstra, MF de Boer, I Bruaset, JA van Oostayen, JS Lameris, RH Kruyt, FB Joosten, JH van Krieken, FT Bosman, SC Henzen-Logmans, JM Wiersma-van Tilburg, J Hermans and RJ Baatenburg de Jong
Department of Otolaryngology, University Hospital Leiden, The Netherlands.

PURPOSE: To verify the acclaimed accuracy of ultrasound (US) combined with US-guided fine-needle aspiration biopsy (FNAB) in the detection of lymph node metastasis in the neck and to evaluate the interobserver variability. MATERIALS AND METHODS: In a prospective, multicenter study of 185 patients with head and neck squamous cell carcinoma, US (n=238 neck sides) with US-guided FNAB (n=178 neck sides) was used for evaluation of the lymph node status of the neck. Findings were correlated with those of histopathologic examination in 238 neck sides. RESULTS: US with US-guided FNAB had a sensitivity of 77% and a specificity of 100%. Nineteen of 178 aspirations were nondiagnostic. There were no significant differences between the four participating hospitals or the individual sonologists (P>.05). CONCLUSION: Sensitivity of US with US-guided FNAB was slightly lower compared with previous reports. Specificity was similar to previous reports. Interobserver variability appeared to be low. The validity of US with US-guided FNAB is high and warrants widespread use of the procedure for evaluation of the neck.

This article has been cited by other articles:

				M. Soudack, R. B. Shalom, O. Israel, Y. Ben-Arie, Z. Levy, and D. Gaitini Utility of Sonographically Guided Biopsy in Metabolically Suspected Recurrent Lymphoma J. Ultrasound Med., February 1, 2008; 27(2): 225 - 231. [Abstract] [Full Text] [PDF]

				L. N. Nazarian Can Sonoelastography Enable Reliable Differentiation between Benign and Metastatic Cervical Lymph Nodes? Radiology, April 1, 2007; 243(1): 1 - 2. [Full Text] [PDF]

				G. L. Ross, D. S. Soutar, D. Gordon MacDonald, T. Shoaib, I. Camilleri, A. G. Roberton, J. A. Sorensen, J. Thomsen, P. Grupe, J. Alvarez, et al. Sentinel Node Biopsy in Head and Neck Cancer: Preliminary Results of a Multicenter Trial Ann. Surg. Oncol., July 1, 2004; 11(7): 690 - 696. [Abstract] [Full Text] [PDF]

				G.L. Ross, D.S. Soutar, D.G. MacDonald, T. Shoaib, I.G. Camilleri, and A.G. Robertson Improved Staging of Cervical Metastases in Clinically Node-Negative Patients With Head and Neck Squamous Cell Carcinoma Ann. Surg. Oncol., February 1, 2004; 11(2): 213 - 218. [Abstract] [Full Text] [PDF]

				M. Sumi, N. Sakihama, T. Sumi, M. Morikawa, M. Uetani, H. Kabasawa, K. Shigeno, K. Hayashi, H. Takahashi, and T. Nakamura Discrimination of Metastatic Cervical Lymph Nodes with Diffusion-Weighted MR Imaging in Patients with Head and Neck Cancer AJNR Am. J. Neuroradiol., September 1, 2003; 24(8): 1627 - 1634. [Abstract] [Full Text] [PDF]

				N. J. Screaton, L. H. Berman, and J. W. Grant Head and Neck Lymphadenopathy: Evaluation with US-guided Cutting-Needle Biopsy Radiology, July 1, 2002; 224(1): 75 - 81. [Abstract] [Full Text]

				G.L. Ross, T. Shoaib, D.S. Soutar, D.G. MacDonald, I.G. Camilleri, R.G. Bessent, and H.W. Gray The First International Conference on Sentinel Node Biopsy in Mucosal Head and Neck Cancer and Adoption of a Multicenter Trial Protocol Ann. Surg. Oncol., May 1, 2002; 9(4): 406 - 410. [Abstract] [Full Text] [PDF]

				R. P. Takes, R. J. Baatenburg de Jong, M. J. R. C. Alles, C. A. Meeuwis, H. A. M. Marres, P. P. M. Knegt, G. B. de la Riviere, P. C. M. de Wilde, W. J. Mooi, J. Hermans, et al. Markers for Nodal Metastasis in Head and Neck Squamous Cell Cancer Arch Otolaryngol Head Neck Surg, May 1, 2002; 128(5): 512 - 518. [Abstract] [Full Text] [PDF]

				J. A. Castelijns and M. W. M. van den Brekel Detection of Lymph Node Metastases in the Neck: Radiologic Criteria AJNR Am. J. Neuroradiol., January 1, 2001; 22(1): 3 - 4. [Full Text] [PDF]

				K. Yonetsu, M. Sumi, M. Izumi, M. Ohki, S. Eida, and T. Nakamura Contribution of Doppler Sonography Blood Flow Information to the Diagnosis of Metastatic Cervical Nodes in Patients with Head and Neck Cancer: Assessment in Relation to Anatomic Levels of the Neck AJNR Am. J. Neuroradiol., January 1, 2001; 22(1): 163 - 169. [Abstract] [Full Text] [PDF]

				M. W. M. van den Brekel, J. A. Castelijns, L. C. Reitsma, C. R. Leemans, I. van der Waal, and G. B. Snow Outcome of Observing the N0 Neck Using Ultrasonographic-Guided Cytology for Follow-up Arch Otolaryngol Head Neck Surg, February 1, 1999; 125(2): 153 - 156. [Abstract] [Full Text] [PDF]