Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yamashita, Y.
Right arrow Articles by Takahashi, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yamashita, Y.
Right arrow Articles by Takahashi, M.

Radiology, Vol 200, 79-84, Copyright © 1996 by Radiological Society of North America

ARTICLES

Small hepatocellular carcinoma in patients with chronic liver damage: prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver

Y Yamashita, K Mitsuzaki, T Yi, I Ogata, T Nishiharu, J Urata and M Takahashi
Department of Radiology, Kumamoto University School of Medicine, Japan.

PURPOSE: To compare contrast material-enhanced dynamic magnetic resonance (MR) imaging with helical computed tomography (CT) for the detection of small hepatocellular carcinoma (HCC) in patients with chronic liver damage. MATERIALS AND METHODS: Fifty patients with chronic hepatitis or liver cirrhosis underwent dynamic contrast- enhanced fast low-angle shot MR imaging and multiple-phase helical CT. Arterial, portal-venous, and delayed-phase images were compared. Diagnostic ability with both techniques was evaluated by means of receiver operating characteristic (ROC) analysis; images in patients with (n = 27) and those without (n = 15) HCC in whom the same anatomic levels were available for both examinations were assessed. Seventy-two lesions were evaluated, and tumor diameter ranged from 0.5 to 3.0 cm (mean, 1.9 cm). RESULTS: ROC analysis showed that the arterial-phase images obtained with both techniques allowed better detection of HCC. Diagnostic ability was significantly better with arterial-phase MR imaging (mean area under the ROC curve [Az] = 0.96) than arterial-phase CT (Az = 0.87) or with images from any other phase (P < .05). For the delayed phase, diagnostic capability was significantly better with CT (Az = 0.84) than with MR imaging (Az = 0.77) (P < .05). CONCLUSION: Arterial-phase dynamic MR imaging is superior to helical CT for the detection of HCC in patients with chronic liver damage.


This article has been cited by other articles:


Home page
 Am. J. Roentgenol.Home page
S. H. Choi, J. M. Lee, N. C. Yu, K.-S. Suh, J.-J. Jang, S. H. Kim, and B. I. Choi
Hepatocellular Carcinoma in Liver Transplantation Candidates: Detection with Gadobenate Dimeglumine-Enhanced MRI
Am. J. Roentgenol., August 1, 2008; 191(2): 529 - 536.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
M. Okada, T. Murakami, S. Kumano, I. Imaoka, T. Shimono, R. Ashikaga, and M. Hosono
Comparison Between One-Route and Two-Route Injection for Liver and Aortic Enhancement Using MDCT
Am. J. Roentgenol., June 1, 2008; 190(6): W323 - W326.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
J. M. Willatt, H. K. Hussain, S. Adusumilli, and J. A. Marrero
MR Imaging of Hepatocellular Carcinoma in the Cirrhotic Liver: Challenges and Controversies
Radiology, May 1, 2008; 247(2): 311 - 330.
[Abstract] [Full Text] [PDF]

Home page
 RadioGraphicsHome page
R. F. Hanna, D. A. Aguirre, N. Kased, S. C. Emery, M. R. Peterson, and C. B. Sirlin
Cirrhosis-associated Hepatocellular Nodules: Correlation of Histopathologic and MR Imaging Features
RadioGraphics, May 1, 2008; 28(3): 747 - 769.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Surg. Oncol.Home page
T. Takayama, M. Makuuchi, M. Kojiro, G. Y. Lauwers, R. B. Adams, S. R. Wilson, H.-J. Jang, C. Charnsangavej, and B. Taouli
Early Hepatocellular Carcinoma: Pathology, Imaging, and Therapy
Ann. Surg. Oncol., April 1, 2008; 15(4): 972 - 978.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
S. H. Kim, Y. J. Kim, J. M. Lee, K. D. Choi, Y. J. Chung, J. K. Han, J. Y. Lee, M. W. Lee, C. J. Han, J. I. Choi, et al.
Esophageal Varices in Patients with Cirrhosis: Multidetector CT Esophagography--Comparison with Endoscopy
Radiology, March 1, 2007; 242(3): 759 - 768.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
Y. K. Kim, C. S. Kim, G. H. Chung, Y.-M. Han, S. Y. Lee, S. B. Chon, and J. M. Lee
Comparison of Gadobenate Dimeglumine-Enhanced Dynamic MRI and 16-MDCT for the Detection of Hepatocellular Carcinoma
Am. J. Roentgenol., January 1, 2006; 186(1): 149 - 157.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
A. E. Holland, E. M. Hecht, W. Y. Hahn, D. C. Kim, J. S. Babb, V. S. Lee, A. B. West, and G. A. Krinsky
Importance of Small (<=20-mm) Enhancing Lesions Seen Only during the Hepatic Arterial Phase at MR Imaging of the Cirrhotic Liver: Evaluation and Comparison with Whole Explanted Liver
Radiology, December 1, 2005; 237(3): 938 - 944.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
Y. Funama, K. Awai, Y. Nakayama, K. Kakei, N. Nagasue, M. Shimamura, N. Sato, S. Sultana, S. Morishita, and Y. Yamashita
Radiation Dose Reduction without Degradation of Low-Contrast Detectability at Abdominal Multisection CT with a Low-Tube Voltage Technique: Phantom Study
Radiology, December 1, 2005; 237(3): 905 - 910.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
J. Ward, P. J. Robinson, J. A. Guthrie, S. Downing, D. Wilson, J. P. A. Lodge, K. R. Prasad, G. J. Toogood, and J. I. Wyatt
Liver Metastases in Candidates for Hepatic Resection: Comparison of Helical CT and Gadolinium- and SPIO-enhanced MR Imaging
Radiology, October 1, 2005; 237(1): 170 - 180.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
K. Mori, H. Yoshioka, N. Takahashi, M. Yamaguchi, T. Ueno, T. Yamaki, and Y. Saida
Triple Arterial Phase Dynamic MRI with Sensitivity Encoding for Hypervascular Hepatocellular Carcinoma: Comparison of the Diagnostic Accuracy Among the Early, Middle, Late, and Whole Triple Arterial Phase Imaging
Am. J. Roentgenol., January 1, 2005; 184(1): 63 - 69.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
K. Ito, T. Fujita, A. Shimizu, S. Koike, K. Sasaki, N. Matsunaga, S. Hibino, and M. Yuhara
Multiarterial Phase Dynamic MRI of Small Early Enhancing Hepatic Lesions in Cirrhosis or Chronic Hepatitis: Differentiating Between Hypervascular Hepatocellular Carcinomas and Pseudolesions
Am. J. Roentgenol., September 1, 2004; 183(3): 699 - 705.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
H. K. Hussain, I. Syed, H. V. Nghiem, T. D. Johnson, R. C. Carlos, W. J. Weadock, and I. R. Francis
T2-weighted MR Imaging in the Assessment of Cirrhotic Liver
Radiology, March 1, 2004; 230(3): 637 - 644.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
R. C. Carlos, H. M. Kim, H. K. Hussain, I. R. Francis, H. V. Nghiem, and A. M. Fendrick
Developing a Prediction Rule to Assess Hepatic Malignancy in Patients with Cirrhosis
Am. J. Roentgenol., April 1, 2003; 180(4): 893 - 900.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
Y. Noguchi, T. Murakami, T. Kim, M. Hori, K. Osuga, S. Kawata, S. Kumano, A. Okada, T. Sugiura, and H. Nakamura
Detection of Hepatocellular Carcinoma: Comparison of Dynamic MR Imaging with Dynamic Double Arterial Phase Helical CT
Am. J. Roentgenol., February 1, 2003; 180(2): 455 - 460.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
M. Matsuo, M. Kanematsu, T. Kim, M. Hori, M. Takamura, T. Murakami, H. Kondo, N. Moriyama, H. Nakamura, and H. Hoshi
Esophageal Varices: Diagnosis with Gadolinium-Enhanced MR Imaging of the Liver for Patients with Chronic Liver Damage
Am. J. Roentgenol., February 1, 2003; 180(2): 461 - 466.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
S. A. Teefey, C. C. Hildeboldt, F. Dehdashti, B. A. Siegel, M. G. Peters, J. P. Heiken, J. J. Brown, E. G. McFarland, W. D. Middleton, D. M. Balfe, et al.
Detection of Primary Hepatic Malignancy in Liver Transplant Candidates: Prospective Comparison of CT, MR Imaging, US, and PET
Radiology, February 1, 2003; 226(2): 533 - 542.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
A. Shimizu, K. Ito, S. Koike, T. Fujita, K. Shimizu, and N. Matsunaga
Cirrhosis or Chronic Hepatitis: Evaluation of Small (<=2-cm) Early-Enhancing Hepatic Lesions with Serial Contrast-enhanced Dynamic MR Imaging
Radiology, February 1, 2003; 226(2): 550 - 555.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
M. Kanematsu, R. C. Semelka, M. Matsuo, H. Kondo, M. Enya, S. Goshima, N. Moriyama, and H. Hoshi
Gadolinium-enhanced MR Imaging of the Liver: Optimizing Imaging Delay for Hepatic Arterial and Portal Venous Phases—A Prospective Randomized Study in Patients with Chronic Liver Damage
Radiology, November 1, 2002; 225(2): 407 - 415.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
X.-M. Zhang, D. G. Mitchell, H. Shi, G. A. Holland, L. Parker, S. K. Herrine, D. Pasqualin, and R. Rubin
Chronic Hepatitis C Activity: Correlation with Lymphadenopathy on MR Imaging
Am. J. Roentgenol., August 1, 2002; 179(2): 417 - 422.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
S. Kawata, T. Murakami, T. Kim, M. Hori, M. P. Federle, S. Kumano, E. Sugihara, S. Makino, H. Nakamura, and M. Kudo
Multidetector CT: Diagnostic Impact of Slice Thickness on Detection of Hypervascular Hepatocellular Carcinoma
Am. J. Roentgenol., July 1, 2002; 179(1): 61 - 66.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
G. L. Bennett, G. A. Krinsky, R. J. Abitbol, S. Y. Kim, N. D. Theise, and L. W. Teperman
Sonographic Detection of Hepatocellular Carcinoma and Dysplastic Nodules in Cirrhosis: Correlation of Pretransplantation Sonography and Liver Explant Pathology in 200 Patients
Am. J. Roentgenol., July 1, 2002; 179(1): 75 - 80.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
Y. Y. Jeong, D. G. Mitchell, and T. Kamishima
Small (<20 mm) Enhancing Hepatic Nodules Seen on Arterial Phase MR Imaging of the Cirrhotic Liver: Clinical Implications
Am. J. Roentgenol., June 1, 2002; 178(6): 1327 - 1334.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
M. Oudkerk, C. G. Torres, B. Song, M. Konig, J. Grimm, J. Fernandez-Cuadrado, B. Op de Beeck, M. Marquardt, P. van Dijk, and J. C. de Groot
Characterization of Liver Lesions with Mangafodipir Trisodium-enhanced MR Imaging: Multicenter Study Comparing MR and Dual-Phase Spiral CT
Radiology, May 1, 2002; 223(2): 517 - 524.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
T. Kim, T. Murakami, M. Hori, M. Takamura, S. Takahashi, A. Okada, S. Kawata, M. Cruz, M. P. Federle, and H. Nakamura
Small Hypervascular Hepatocellular Carcinoma Revealed by Double Arterial Phase CT Performed with Single Breath-Hold Scanning and Automatic Bolus Tracking
Am. J. Roentgenol., April 1, 2002; 178(4): 899 - 904.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
C. H. Coulam, F. P. Chan, and K. C. P. Li
Can a Multiphasic Contrast-Enhanced Three-Dimensional Fast Spoiled Gradient-Recalled Echo Sequence Be Sufficient for Liver MR Imaging?
Am. J. Roentgenol., February 1, 2002; 178(2): 335 - 341.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
Y. Maetani, K. Itoh, C. Watanabe, T. Shibata, F. Ametani, H. Yamabe, and J. Konishi
MR Imaging of Intrahepatic Cholangiocarcinoma with Pathologic Correlation
Am. J. Roentgenol., June 1, 2001; 176(6): 1499 - 1507.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
G. A. Krinsky, V. S. Lee, N. D. Theise, J. C. Weinreb, N. M. Rofsky, T. Diflo, and L. W. Teperman
Hepatocellular Carcinoma and Dysplastic Nodules in Patients with Cirrhosis: Prospective Diagnosis with MR Imaging and Explantation Correlation
Radiology, May 1, 2001; 219(2): 445 - 454.
[Abstract] [Full Text]

Home page
 RadiologyHome page
R. C. Semelka and T. K. G. Helmberger
Contrast Agents for MR Imaging of the Liver
Radiology, January 1, 2001; 218(1): 27 - 38.
[Abstract] [Full Text]

Home page
 RadiologyHome page
J. Ward, J. A. Guthrie, D. J. Scott, J. Atchley, D. Wilson, M. H. Davies, J. I. Wyatt, and P. J. Robinson
Hepatocellular Carcinoma in the Cirrhotic Liver: Double-Contrast MR Imaging for Diagnosis
Radiology, July 1, 2000; 216(1): 154 - 162.
[Abstract] [Full Text]

Home page
 RadiologyHome page
V. S. Lee, M. T. Lavelle, N. M. Rofsky, G. Laub, D. M. Thomasson, G. A. Krinsky, and J. C. Weinreb
Hepatic MR Imaging with a Dynamic Contrast-enhanced Isotropic Volumetric Interpolated Breath-hold Examination: Feasibility, Reproducibility, and Technical Quality
Radiology, May 1, 2000; 215(2): 365 - 372.
[Abstract] [Full Text]

Home page
 RadiologyHome page
K. Ito, R. Blasbalg, S. M. Hussain, and D. G. Mitchell
Portal Vein and Its Tributaries: Evaluation with Thin-Section Three-dimensional Contrast-enhanced Dynamic Fat-suppressed MR Imaging
Radiology, May 1, 2000; 215(2): 381 - 386.
[Abstract] [Full Text]

Home page
 Postgrad. Med. J.Home page
S. Badvie
Hepatocellular carcinoma
Postgrad. Med. J., January 1, 2000; 76(891): 4 - 11.
[Abstract] [Full Text]

Home page
 RadiologyHome page
K. Ito, D. G. Mitchell, T. Gabata, H.-W. L. Hann, P. N. Kim, T. Fujita, H. Awaya, K. Honjo, and N. Matsunaga
Hepatocellular Carcinoma: Association with Increased Iron Deposition in the Cirrhotic Liver at MR Imaging
Radiology, July 1, 1999; 212(1): 235 - 240.
[Abstract] [Full Text]

Home page
 RadiologyHome page
R. N. Low, R. C. Semelka, S. Worawattanakul, G. D. Alzate, and J. S. Sigeti
Extrahepatic Abdominal Imaging in Patients with Malignancy: Comparison of MR Imaging and Helical CT, with Subsequent Surgical Correlation
Radiology, March 1, 1999; 210(3): 625 - 632.
[Abstract] [Full Text]

Home page
 RadiologyHome page
C. B. Winston, L. H. Schwartz, Y. Fong, L. H. Blumgart, and D. M. Panicek
Hepatocellular Carcinoma: MR Imaging Findings in Cirrhotic Livers and Noncirrhotic Livers
Radiology, January 1, 1999; 210(1): 75 - 79.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1996 by the Radiological Society of North America.