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Radiology, Vol 200, 553-558, Copyright © 1996 by Radiological Society of North America
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JR MacFall, HC Charles, RD Black, H Middleton, JC Swartz, B Saam, B Driehuys, C Erickson, W Happer, GD Cates, GA Johnson and CE Ravin
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
Two healthy volunteers who had inhaled approximately 0.75 L of laser- polarized helium-3 gas underwent magnetic resonance imaging at 1.5 T with fast gradient-echo pulse sequences and small flip angles ( < 10 degrees). Thick-section (20 mm) coronal images, time-course data (30 images collected every 1.8 seconds), and thin-section (6 mm) images were acquired. Subjects were able to breathe the gas (12% polarization) without difficulty. Thick-section images were of good quality and had a signal-to-noise ratio (S/N) of 32:1 near the surface coil and 16:1 farther away. The time images showed regional differences, which indicated potential value for quantitation. High-resolution images showed greater detail and a S/N of approximately 6:1.
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