| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Radiology, Vol 200, 639-649, Copyright © 1996 by Radiological Society of North America
ARTICLES |
LD Buadu, J Murakami, S Murayama, N Hashiguchi, S Sakai, K Masuda, S Toyoshima, S Kuroki and S Ohno
Department of Radiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
PURPOSE: To compare qualitative and quantitative magnetic resonance (MR) mammographic features of breast lesions with histopathologic findings, especially tumor angiogenesis. MATERIALS AND METHODS: Seventy- three patients (72 women, one man; aged 30-78 years; mean age, 51.0 years) with suspicious breast lesions underwent MR imaging. Noncontrast medium-enhanced localization imaging and then gadolinium-enhanced dynamic fast spoiled gradient-recalled-echo (SPGR) imaging were performed in all patients. In selected patients, subtraction fast SPGR images were obtained. The Pearson and Spearman correlation tests were used to determine the strength of the relationships between enhancement parameters and microvessel determinations. RESULTS: Time intensity curve type correlated with microvessel density grade (Spearman rank correlation test: r = .90, P < .001). The steepest slope of contrast medium uptake correlated with microvessel counts (Pearson correlation test; r = .83, P < .001). Peripheral enhancement in invasive carcinomas (n = 9) correlated with high peripheral and low central microvessel densities, which were associated with desmoplasia and/or necrosis. Internal septations (n = 2) were seen only in fibroadenomas. CONCLUSION: The density and distribution of microvessels may play major roles in the determination of the initial rate of contrast medium uptake and the heterogeneity of tumor enhancement.
This article has been cited by other articles:
|
|
 |
|
  S. A. Jansen, G. M. Newstead, H. Abe, A. Shimauchi, R. A. Schmidt, and G. S. Karczmar Pure Ductal Carcinoma in Situ: Kinetic and Morphologic MR Characteristics Compared with Mammographic Appearance and Nuclear Grade Radiology, December 1, 2007; 245(3): 684 - 691. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. H. G. M. Peters, I. H. M. Borel Rinkes, N. P. A. Zuithoff, W. P. T. M. Mali, K. G. M. Moons, and P. H. M. Peeters Meta-Analysis of MR Imaging in the Diagnosis of Breast Lesions Radiology, December 1, 2007; 246(1): 116 - 124. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Kuhl The Current Status of Breast MR Imaging * Part I. Choice of Technique, Image Interpretation, Diagnostic Accuracy, and Transfer to Clinical Practice Radiology, August 1, 2007; 244(2): 356 - 378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Matuszewski, T. Persigehl, A. Wall, N. Meier, R. Bieker, H. Kooijman, B. Tombach, R. Mesters, W. E. Berdel, W. Heindel, et al. Assessment of Bone Marrow Angiogenesis in Patients with Acute Myeloid Leukemia by Using Contrast-enhanced MR Imaging with Clinically Approved Iron Oxides: Initial Experience Radiology, December 1, 2006; 242(1): 217 - 224. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Dromain, C. Balleyguier, S. Muller, M.-C. Mathieu, F. Rochard, P. Opolon, and R. Sigal Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography. Am. J. Roentgenol., November 1, 2006; 187(5): W528 - W537. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Narisada, T. Aoki, T. Sasaguri, H. Hashimoto, T. Konishi, M. Morita, and Y. Korogi Correlation between numeric gadolinium-enhanced dynamic MRI ratios and prognostic factors and histologic type of breast carcinoma. Am. J. Roentgenol., August 1, 2006; 187(2): 297 - 306. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Hylton Dynamic Contrast-Enhanced Magnetic Resonance Imaging As an Imaging Biomarker J. Clin. Oncol., July 10, 2006; 24(20): 3293 - 3298. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Wang, P. Q. Min, P. J. Wang, W. X. Cheng, X. H. Zhang, Y. Wang, X. H. Zhao, and X. Q. Mao Dynamic CT Evaluation of Tumor Vascularity in Renal Cell Carcinoma. Am. J. Roentgenol., May 1, 2006; 186(5): 1423 - 1430. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Teifke, O. Behr, M. Schmidt, A. Victor, T. W. Vomweg, M. Thelen, and H.-A. Lehr Dynamic MR Imaging of Breast Lesions: Correlation with Microvessel Distribution Pattern and Histologic Characteristics of Prognosis Radiology, May 1, 2006; 239(2): 351 - 360. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Doria, M. Noseworthy, W. Oakden, R. Moineddin, T. Rayner, V. Tassos, D. Engelberts, K. Pritzker, M. Rogers, R. Jong, et al. Dynamic contrast-enhanced MRI quantification of synovium microcirculation in experimental arthritis. Am. J. Roentgenol., April 1, 2006; 186(4): 1165 - 1171. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Wurdinger, A. B. Herzog, D. R. Fischer, C. Marx, G. Raabe, A. Schneider, and W. A. Kaiser Differentiation of Phyllodes Breast Tumors from Fibroadenomas on MRI Am. J. Roentgenol., November 1, 2005; 185(5): 1317 - 1321. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Motoori, Y. Iida, Y. Nagai, S. Yamamoto, T. Ueda, H. Funatsu, H. Ito, and O. Yoshitaka MR Imaging of Salivary Duct Carcinoma AJNR Am. J. Neuroradiol., May 1, 2005; 26(5): 1201 - 1206. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. El Khoury, V. Servois, F. Thibault, A. Tardivon, L. Ollivier, M. Meunier, C. Allonier, and S. Neuenschwander MR Quantification of the Washout Changes in Breast Tumors Under Preoperative Chemotherapy: Feasibility and Preliminary Results Am. J. Roentgenol., May 1, 2005; 184(5): 1499 - 1504. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. C. Miller, H. H. Pien, D. Sahani, A. G. Sorensen, and J. H. Thrall Imaging Angiogenesis: Applications and Potential for Drug Development J Natl Cancer Inst, February 2, 2005; 97(3): 172 - 187. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Rehman and G. C. Jayson Molecular Imaging of Antiangiogenic Agents Oncologist, February 1, 2005; 10(2): 92 - 103. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. F. Jordan, M. Runquist, N. Raghunand, R. J. Gillies, W. R. Tate, G. Powis, and A. F. Baker The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging Clin. Cancer Res., January 15, 2005; 11(2): 529 - 536. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. H. Dennis Cheong, C. C. Tchoyoson Lim, and T. S. Koh Dynamic Contrast-enhanced CT of Intracranial Meningioma: Comparison of Distributed and Compartmental Tracer Kinetic Models--Initial Results Radiology, September 1, 2004; 232(3): 921 - 930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. E. Daldrup-Link, J. Rydland, T. H. Helbich, A. Bjornerud, K. Turetschek, K. A. Kvistad, E. Kaindl, T. M. Link, K. Staudacher, D. Shames, et al. Quantification of Breast Tumor Microvascular Permeability with Feruglose-enhanced MR Imaging: Initial Phase II Multicenter Trial Radiology, December 1, 2003; 229(3): 885 - 892. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Morgan, A. L. Thomas, J. Drevs, J. Hennig, M. Buchert, A. Jivan, M. A. Horsfield, K. Mross, H. A. Ball, L. Lee, et al. Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I Studies J. Clin. Oncol., November 1, 2003; 21(21): 3955 - 3964. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Lewin, P. K. Isaacs, V. Vance, and F. J. Larke Dual-Energy Contrast-enhanced Digital Subtraction Mammography: Feasibility Radiology, October 1, 2003; 229(1): 261 - 268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Fujimoto, T. Abe, N. L. Muller, H. Terasaki, S. Kato, J. Sadohara, R. Kono, O. Edamitsu, T. Ishitake, A. Hayashi, et al. Small Peripheral Pulmonary Carcinomas Evaluated with Dynamic MR Imaging: Correlation with Tumor Vascularity and Prognosis Radiology, June 1, 2003; 227(3): 786 - 793. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. G. Redman, P. Esper, Q. Pan, R. L. Dunn, H. K. Hussain, T. Chenevert, G. J. Brewer, and S. D. Merajver Phase II Trial of Tetrathiomolybdate in Patients with Advanced Kidney Cancer Clin. Cancer Res., May 1, 2003; 9(5): 1666 - 1672. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Yabuuchi, T. Fukuya, T. Tajima, Y. Hachitanda, K. Tomita, and M. Koga Salivary Gland Tumors: Diagnostic Value of Gadolinium-enhanced Dynamic MR Imaging with Histopathologic Correlation Radiology, February 1, 2003; 226(2): 345 - 354. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Moulopoulos, T. G. Maris, N. Papanikolaou, G. Panagi, L. Vlahos, and M. A. Dimopoulos Detection of malignant bone marrow involvement with dynamic contrast-enhanced magnetic resonance imaging Ann. Onc., January 1, 2003; 14(1): 152 - 158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. SINHA and U. SINHA Functional Magnetic Resonance of Human Breast Tumors: Diffusion and Perfusion Imaging Ann. N.Y. Acad. Sci., December 1, 2002; 980(1): 95 - 115. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Liberman, E. A. Morris, M. J.-Y. Lee, J. B. Kaplan, L. R. LaTrenta, J. H. Menell, A. F. Abramson, S. M. Dashnaw, D. J. Ballon, and D. D. Dershaw Breast Lesions Detected on MR Imaging: Features and Positive Predictive Value Am. J. Roentgenol., July 1, 2002; 179(1): 171 - 178. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Kishimoto, Y. Watanabe, and M. Shimizu Best Cases from the AFIP: Invasive Ductal Carcinoma with Osteoclast-like Giant Cells RadioGraphics, May 1, 2002; 22(3): 691 - 695. [Full Text] [PDF]
|
|
|
|
|
|
B. S. Kuszyk, F. M. Corl, F. N. Franano, D. A. Bluemke, L. V. Hofmann, B. J. Fortman, and E. K. Fishman Tumor Transport Physiology: Implications for Imaging and Imaging-Guided Therapy Am. J. Roentgenol., October 1, 2001; 177(4): 747 - 753. [Full Text] [PDF]
|
|
|
|
|
|
S. G. Orel and M. D. Schnall MR Imaging of the Breast for the Detection, Diagnosis, and Staging of Breast Cancer Radiology, July 1, 2001; 220(1): 13 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Matsubayashi, Y. Matsuo, G. Edakuni, T. Satoh, O. Tokunaga, and S. Kudo Breast Masses with Peripheral Rim Enhancement on Dynamic Contrast-enhanced MR Images: Correlation of MR Findings with Histologic Features and Expression of Growth Factors Radiology, December 1, 2000; 217(3): 841 - 848. [Abstract] [Full Text]
|
|
|
|
|
|
C. K. Kuhl, P. Mielcareck, S. Klaschik, C. Leutner, E. Wardelmann, J. Gieseke, and H. H. Schild Dynamic Breast MR Imaging: Are Signal Intensity Time Course Data Useful for Differential Diagnosis of Enhancing Lesions? Radiology, April 1, 1999; 211(1): 101 - 110. [Abstract] [Full Text]
|
|
|
|
 |
|
 V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement PNAS, March 14, 2000; 97(6): 2767 - 2772. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| RADIOLOGY | RADIOGRAPHICS | RSNA JOURNALS ONLINE |
