| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Radiology, Vol 202, 227-231, Copyright © 1997 by Radiological Society of North America
ARTICLES |
JJ Mukherjee, PD Peppercorn, RH Reznek, V Patel, G Kaltsas, M Besser and AB Grossman
Department of Endocrinology, St Bartholomew's Hospital, London, England.
PURPOSE: To study the catecholamine-releasing effect of peripheral intravenous administration of the nonionic contrast medium iohexol in patients with pheochromocytomas. MATERIALS AND METHODS: Ten patients (eight women, two men; mean age, 44 years; age range, 25-70 years) with pheochromocytomas and related tumors and six healthy volunteers (five men, one woman; mean age, 31 years; age range, 27-35 years) were examined. Plasma catecholamine levels were measured at intervals for 60 minutes after the injection of 0.9% saline or iohexol on 2 separate days. All 10 patients intravenously received the specific alpha- adrenergic blocker phenoxybenzamine hydrochloride (0.5 mg/kg in 250 mL of 5% dextrose infused over 2 hours) 24 hours before iohexol-enhanced computed tomography. RESULTS: There was no statistically significant increase in epinephrine or norepinephrine levels in the patients or the control subjects. CONCLUSION: While it may be prudent to administer oral alpha- and beta-adrenoceptor antagonists in all patients with a biochemically proved pheochromocytoma to control their symptoms and to prevent a spontaneous adrenergic crisis, specific blockade may not be required before contrast medium-enhanced scanning with iohexol. Although the sample size of this study is relatively small, the results do suggest that in an incidentally detected, clinically silent adrenal mass that may or may not be hypersecreting, the nonionic contrast medium iohexol may be used for scanning without blockade.
This article has been cited by other articles:
|
|
 |
|
  S. K. Baid, E. W. Lai, R. A. Wesley, A. Ling, H. J.L.M. Timmers, K. T. Adams, A. Kozupa, and K. Pacak Brief Communication: Radiographic Contrast Infusion and Catecholamine Release in Patients With Pheochromocytoma Ann Intern Med, January 6, 2009; 150(1): 27 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. W. L. Boland, M. A. Blake, P. F. Hahn, and W. W. Mayo-Smith Incidental Adrenal Lesions: Principles, Techniques, and Algorithms for Imaging Characterization Radiology, December 1, 2008; 249(3): 756 - 775. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L Rosas, A. A Kasperlik-Zaluska, L. Papierska, B. L. Bass, K. Pacak, and G. Eisenhofer Pheochromocytoma crisis induced by glucocorticoids: a report of four cases and review of the literature Eur. J. Endocrinol., March 1, 2008; 158(3): 423 - 429. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Pacak Preoperative Management of the Pheochromocytoma Patient J. Clin. Endocrinol. Metab., November 1, 2007; 92(11): 4069 - 4079. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Bessell-Browne and M. E. O'Malley CT of Pheochromocytoma and Paraganglioma: Risk of Adverse Events with IV Administration of Nonionic Contrast Material Am. J. Roentgenol., April 1, 2007; 188(4): 970 - 974. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. F. Scarsbrook, R. V. Thakker, J. A. H. Wass, F. V. Gleeson, and R. R. Phillips Multiple Endocrine Neoplasia: Spectrum of Radiologic Appearances and Discussion of a Multitechnique Imaging Approach. RadioGraphics, March 1, 2006; 26(2): 433 - 451. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Blake, M. K. Kalra, A. T. Sweeney, B. C. Lucey, M. M. Maher, D. V. Sahani, E. F. Halpern, P. R. Mueller, P. F. Hahn, and G. W. Boland Distinguishing Benign from Malignant Adrenal Masses: Multi-Detector Row CT Protocol with 10-Minute Delay Radiology, December 21, 2005; (2005) 2382041514. [Abstract] [Full Text]
|
|
|
|
|
|
M. A. Blake, M. K. Kalra, M. M. Maher, D. V. Sahani, A. T. Sweeney, P. R. Mueller, P. F. Hahn, and G. W. Boland Pheochromocytoma: An Imaging Chameleon RadioGraphics, October 1, 2004; 24(suppl_1): S87 - S99. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. A. Kaltsas, G. M. Besser, and A. B. Grossman The Diagnosis and Medical Management of Advanced Neuroendocrine Tumors Endocr. Rev., June 1, 2004; 25(3): 458 - 511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Ilias and K. Pacak Current Approaches and Recommended Algorithm for the Diagnostic Localization of Pheochromocytoma J. Clin. Endocrinol. Metab., February 1, 2004; 89(2): 479 - 491. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Blake, S. K. Krishnamoorthy, G. W. Boland, A. T. Sweeney, M. B. Pitman, M. Harisinghani, P. R. Mueller, and P. F. Hahn Low-Density Pheochromocytoma on CT: A Mimicker of Adrenal Adenoma Am. J. Roentgenol., December 1, 2003; 181(6): 1663 - 1668. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. E. Rha, J. Y. Byun, S. E. Jung, H. J. Chun, H. G. Lee, and J. M. Lee Neurogenic Tumors in the Abdomen: Tumor Types and Imaging Characteristics RadioGraphics, January 1, 2003; 23(1): 29 - 43. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Lee, C. M. Slywotzky, M. T. Lavelle, and R. A. Garcia Best Cases from the AFIP : Cystic Pheochromocytoma RadioGraphics, July 1, 2002; 22(4): 935 - 940. [Full Text] [PDF]
|
|
|
|
 |
|
 A G Rockall and A Sahdev Functioning adrenal pathology Imaging, April 1, 2002; 14(2): 122 - 136. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| RADIOLOGY | RADIOGRAPHICS | RSNA JOURNALS ONLINE |
