Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yue, N. C.
Right arrow Articles by Bryan, R. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yue, N. C.
Right arrow Articles by Bryan, R. N.

Radiology, Vol 202, 33-39, Copyright © 1997 by Radiological Society of North America

ARTICLES

Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the cardiovascular health study

NC Yue, AM Arnold, WT Longstreth Jr, AD Elster, CA Jungreis, DH O'Leary, VC Poirier and RN Bryan
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287-2182, USA.

PURPOSE: To determine the distribution of changes in sulcal size, ventricular size, and white matter signal intensity depicted on cranial magnetic resonance (MR) images, with stratification according to age, race, and sex. MATERIALS AND METHODS: Ventricular size, sulcal size, and white matter signal intensity changes were graded on cranial MR images of 3,660 community-living, elderly participants in the Cardiovascular Health Study. A healthier subgroup was also defined. Summary statistics for both groups were generated for age, race, and sex. RESULTS: Regression models of the entire imaged cohort showed higher grades of all variables with increasing age, and higher ventricular and sulcal grades in men and in nonblack individuals. White matter grade was greater in women and in black individuals. Regression models of the healthier subgroup showed similar associations, except for a lack of association of sulcal and ventricular size with race. CONCLUSION: Sulcal width, ventricular size, and white matter signal intensity change with age, sex, and race. Knowledge of these changes is important in appropriate interpretation of MR images of the elderly.


This article has been cited by other articles:


Home page
 NeurologyHome page
J. K. Virtanen, D. S. Siscovick, W. T. Longstreth Jr, L. H. Kuller, and D. Mozaffarian
Fish consumption and risk of subclinical brain abnormalities on MRI in older adults
Neurology, August 5, 2008; 71(6): 439 - 446.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
A. M. Brickman, N. Schupf, J. J. Manly, J. A. Luchsinger, H. Andrews, M. X. Tang, C. Reitz, S. A. Small, R. Mayeux, C. DeCarli, et al.
Brain Morphology in Older African Americans, Caribbean Hispanics, and Whites From Northern Manhattan
Arch Neurol, August 1, 2008; 65(8): 1053 - 1061.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
L. C. Silbert, C. Nelson, D. B. Howieson, M. M. Moore, and J. A. Kaye
Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline
Neurology, July 8, 2008; 71(2): 108 - 113.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
D. C. Steffens, H. Chung, K. R. R. Krishnan, W.T. Longstreth Jr, M. Carlson, and G. L. Burke
Antidepressant Treatment and Worsening White Matter on Serial Cranial Magnetic Resonance Imaging in the Elderly: The Cardiovascular Health Study
Stroke, March 1, 2008; 39(3): 857 - 862.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
C. Rosano, H. J. Aizenstein, S. Studenski, and A. B. Newman
A Regions-of-Interest Volumetric Analysis of Mobility Limitations in Community-Dwelling Older Adults
J. Gerontol. A Biol. Sci. Med. Sci., September 1, 2007; 62(9): 1048 - 1055.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
V. Hachinski, C. Iadecola, R. C. Petersen, M. M. Breteler, D. L. Nyenhuis, S. E. Black, W. J. Powers, C. DeCarli, J. G. Merino, R. N. Kalaria, et al.
National Institute of Neurological Disorders and Stroke-Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards
Stroke, September 1, 2006; 37(9): 2220 - 2241.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
W. F. Stewart, B. S. Schwartz, C. Davatzikos, D. Shen, D. Liu, X. Wu, A. C. Todd, W. Shi, S. Bassett, and D. Youssem
Past adult lead exposure is linked to neurodegeneration measured by brain MRI
Neurology, May 23, 2006; 66(10): 1476 - 1484.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. PsychiatryHome page
S. H. Woodward, D. G. Kaloupek, C. C. Streeter, M. O. Kimble, A. L. Reiss, S. Eliez, L. L. Wald, P. F. Renshaw, B. B. Frederick, B. Lane, et al.
Hippocampal Volume, PTSD, and Alcoholism in Combat Veterans
Am J Psychiatry, April 1, 2006; 163(4): 674 - 681.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
A. L. DeStefano, L. D. Atwood, J. M. Massaro, N. Heard-Costa, A. Beiser, R. Au, P. A. Wolf, and C. DeCarli
Genome-Wide Scan for White Matter Hyperintensity: The Framingham Heart Study
Stroke, January 1, 2006; 37(1): 77 - 81.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
A. D. Murray, R. T. Staff, S. D. Shenkin, I. J. Deary, J. M. Starr, and L. J. Whalley
Brain White Matter Hyperintensities: Relative Importance of Vascular Risk Factors in Nondemented Elderly People
Radiology, October 1, 2005; 237(1): 251 - 257.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
D. S. Knopman, T. H. Mosley, D. J. Catellier, A. R. Sharrett, and for the Atherosclerosis Risk in Communities (ARIC)
Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort
Neurology, September 27, 2005; 65(6): 876 - 881.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
T. H. Mosley Jr, D. S. Knopman, D. J. Catellier, N. Bryan, R. G. Hutchinson, C. A. Grothues, A. R. Folsom, L. S. Cooper, G. L. Burke, D. Liao, et al.
Cerebral MRI findings and cognitive functioning: The Atherosclerosis Risk in Communities Study
Neurology, June 28, 2005; 64(12): 2056 - 2062.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
M. A. Mohamed, D. M. Yousem, A. Tekes, N. Browner, and V. D. Calhoun
Correlation Between the Amplitude of Cortical Activation and Reaction Time: A Functional MRI Study
Am. J. Roentgenol., September 1, 2004; 183(3): 759 - 765.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
L. H. Kuller, W.T. Longstreth Jr, A. M. Arnold, C. Bernick, R. Nick Bryan, N. J. Beauchamp Jr, and for the Cardiovascular Health Study Collaborative
White Matter Hyperintensity on Cranial Magnetic Resonance Imaging: A Predictor of Stroke
Stroke, August 1, 2004; 35(8): 1821 - 1825.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
L. D. Atwood, P. A. Wolf, N. L. Heard-Costa, J. M. Massaro, A. Beiser, R. B. D'Agostino, and C. DeCarli
Genetic Variation in White Matter Hyperintensity Volume in the Framingham Study
Stroke, July 1, 2004; 35(7): 1609 - 1613.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
D. M. Yousem, R. N. Bryan, N. J. Beauchamp Jr., and A. M. Arnold
A National Neuroimaging Database: A Call to Action
AJNR Am. J. Neuroradiol., June 1, 2004; 25(6): 908 - 909.
[Full Text] [PDF]

Home page
 StrokeHome page
J. Ding, M. L. Eigenbrodt, T. H. Mosley Jr, R. G. Hutchinson, A. R. Folsom, T. B. Harris, and F. J. Nieto
Alcohol Intake and Cerebral Abnormalities on Magnetic Resonance Imaging in a Community-Based Population of Middle-Aged Adults: The Atherosclerosis Risk in Communities (ARIC) Study
Stroke, January 1, 2004; 35(1): 16 - 21.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
T. Y. Wong, T. H. Mosley Jr., R. Klein, B. E.K. Klein, A. R. Sharrett, D. J. Couper, and L. D. Hubbard
Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people
Neurology, September 23, 2003; 61(6): 806 - 811.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
L. S. Babiarz, D. M. Yousem, B. A. Wasserman, C. Wu, W. Bilker, and N. J. Beauchamp Jr.
Cavernous Carotid Artery Calcification and White Matter Ischemia
AJNR Am. J. Neuroradiol., May 1, 2003; 24(5): 872 - 877.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. M. Resnick, D. L. Pham, M. A. Kraut, A. B. Zonderman, and C. Davatzikos
Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain
J. Neurosci., April 15, 2003; 23(8): 3295 - 3301.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
K. J. Mukamal, L. H. Kuller, A. L. Fitzpatrick, W. T. Longstreth Jr, M. A. Mittleman, and D. S. Siscovick
Prospective Study of Alcohol Consumption and Risk of Dementia in Older Adults
JAMA, March 19, 2003; 289(11): 1405 - 1413.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
S. J. Karlik
Visualizing Radiologic Data
Am. J. Roentgenol., March 1, 2003; 180(3): 607 - 619.
[Full Text] [PDF]

Home page
 StrokeHome page
D. C. Steffens, K. R. R. Krishnan, C. Crump, and G. L. Burke
Cerebrovascular Disease and Evolution of Depressive Symptoms in the Cardiovascular Health Study
Stroke, June 1, 2002; 33(6): 1636 - 1644.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
R. J. Havlik, D. J. Foley, B. Sayer, K. Masaki, L. White, and L. J. Launer
Variability in Midlife Systolic Blood Pressure Is Related to Late-Life Brain White Matter Lesions: The Honolulu-Asia Aging Study
Stroke, January 1, 2002; 33(1): 26 - 30.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
S. A. Leaper, A. D. Murray, H. A. Lemmon, R. T. Staff, I. J. Deary, J. R. Crawford, and L. J. Whalley
Neuropsychologic Correlates of Brain White Matter Lesions Depicted on MR Images: 1921 Aberdeen Birth Cohort
Radiology, October 1, 2001; 221(1): 51 - 55.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
K. J. Mukamal, W. T. Longstreth Jr, M. A. Mittleman, R. M. Crum, D. S. Siscovick, and D. Bereczki
Alcohol Consumption and Subclinical Findings on Magnetic Resonance Imaging of the Brain in Older Adults: The Cardiovascular Health Study Editorial Comment: The Cardiovascular Health Study
Stroke, September 1, 2001; 32(9): 1939 - 1946.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
M. Hadjivassiliou, C. L. Tooth, C. A.J. Romanowski, J. Byrne, R. D.E. Battersby, S. Oxbury, C. S. Crewswell, E. Burkitt, N. A. Stokes, C. Paul, et al.
Aneurysmal SAH: Cognitive outcome and structural damage after clipping or coiling
Neurology, June 26, 2001; 56(12): 1672 - 1677.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. PsychiatryHome page
R. D. Nebes, I. J. Vora, C. C. Meltzer, M. B. Fukui, R. L. Williams, M. I. Kamboh, J. Saxton, P. R. Houck, S. T. DeKosky, and C. F. Reynolds III
Relationship of Deep White Matter Hyperintensities and Apolipoprotein E Genotype to Depressive Symptoms in Older Adults Without Clinical Depression
Am J Psychiatry, June 1, 2001; 158(6): 878 - 884.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
W. T. Longstreth Jr, P. Diehr, T. A. Manolio, N. J. Beauchamp, C. A. Jungreis, D. Lefkowitz, and for the Cardiovascular Health Study Collaborative
Cluster Analysis and Patterns of Findings on Cranial Magnetic Resonance Imaging of the Elderly: The Cardiovascular Health Study
Arch Neurol, April 1, 2001; 58(4): 635 - 640.
[Abstract] [Full Text] [PDF]

Home page
 JNMHome page
C. Cidis Meltzer, M. N. Cantwell, P. J. Greer, D. Ben-Eliezer, G. Smith, G. Frank, W. H. Kaye, P. R. Houck, and J. C. Price
Does Cerebral Blood Flow Decline in Healthy Aging? A PET Study with Partial-Volume Correction
J. Nucl. Med., November 1, 2000; 41(11): 1842 - 1848.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
S. M. Resnick, A. F. Goldszal, C. Davatzikos, S. Golski, M. A. Kraut, E. J. Metter, R. N. Bryan, and A. B. Zonderman
One-year Age Changes in MRI Brain Volumes in Older Adults
Cereb Cortex, May 1, 2000; 10(5): 464 - 472.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Coll. Nutr.Home page
L. R. White, H. Petrovitch, G. W. Ross, K. Masaki, J. Hardman, J. Nelson, D. Davis, and W. Markesbery
Brain Aging and Midlife Tofu Consumption
J. Am. Coll. Nutr., April 1, 2000; 19(2): 242 - 255.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
D. C. Steffens, M. J. Helms, K. R. R. Krishnan, and G. L. Burke
Cerebrovascular Disease and Depression Symptoms in the Cardiovascular Health Study
Stroke, October 1, 1999; 30(10): 2159 - 2166.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
G. E. Swan, T. Reed, L. M. Jack, B. L. Miller, T. Markee, P. A. Wolf, C. DeCarli, and D. Carmelli
Differential Genetic Influence for Components of Memory in Aging Adult Twins
Arch Neurol, September 1, 1999; 56(9): 1127 - 1132.
[Abstract] [Full Text] [PDF]

Home page
 Arch Gen PsychiatryHome page
A. Pfefferbaum, E. V. Sullivan, M. J. Rosenbloom, D. H. Mathalon, and K. O. Lim
A Controlled Study of Cortical Gray Matter and Ventricular Changes in Alcoholic Men Over a 5-Year Interval
Arch Gen Psychiatry, October 1, 1998; 55(10): 905 - 912.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
C. E. Coffey, J. F. Lucke, J. A. Saxton, G. Ratcliff, L. J. Unitas, B. Billig, and R. N. Bryan
Sex Differences in Brain Aging: A Quantitative Magnetic Resonance Imaging Study
Arch Neurol, February 1, 1998; 55(2): 169 - 179.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
L. H. Kuller, L. Shemanski, T. Manolio, M. Haan, L. Fried, N. Bryan, G. L. Burke, R. Tracy, and R. Bhadelia
Relationship Between ApoE, MRI Findings, and Cognitive Function in the Cardiovascular Health Study
Stroke, February 1, 1998; 29(2): 388 - 398.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
W. M. Brooks, M. H. Wesley, P. W. Kodituwakku, P. J. Garry, and G. A. Rosenberg
1H-MRS Differentiates White Matter Hyperintensities in Subcortical Arteriosclerotic Encephalopathy From Those in Normal Elderly
Stroke, October 1, 1997; 28(10): 1940 - 1943.
[Abstract] [Full Text]

Home page
 JWatch GeneralHome page
BRAIN MRI FINDINGS IN AN ELDERLY POPULATION
Journal Watch (General), January 28, 1997; 1997(128): 2 - 2.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1997 by the Radiological Society of North America.