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Radiology, Vol 206, 389-391, Copyright © 1998 by Radiological Society of North America

ARTICLES

Alendronate-induced esophagitis: case report of a recently recognized form of severe esophagitis with esophageal stricture--radiographic features

JM Ryan, P Kelsey, BM Ryan and PR Mueller
Department of Radiology, Massachusetts General Hospital, Boston, USA.

Alendronate sodium, an aminobiphosphonate used primarily to treat osteoporosis in postmenopausal women, is known to cause esophagitis. A 71-year-old woman experienced severe, acute esophagitis and severe stricture of the esophagus due to oral alendronate therapy. Unlike in previous cases, she had taken alendronate for 10 months before the onset of complications and the stricture proved resistant to dilation.


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