Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kitagaki, H.
Right arrow Articles by Hata, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kitagaki, H.
Right arrow Articles by Hata, Y.

Radiology, Vol 208, 431-439, Copyright © 1998 by Radiological Society of North America

ARTICLES

Frontotemporal dementia and Alzheimer disease: evaluation of cortical atrophy with automated hemispheric surface display generated with MR images

H Kitagaki, E Mori, S Yamaji, K Ishii, N Hirono, S Kobashi and Y Hata
Neuroimaging Research/Radiology Service, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan.

PURPOSE: To determine the features of cortical atrophy in frontotemporal dementia (FTD) and Alzheimer disease by using a hemispheric surface display generated with magnetic resonance (MR) images. MATERIALS AND METHODS: The extent of cortical atrophy was evaluated with automated MR hemispheric surface display and volumetry in 18 patients with FTD and in 18 matched patients with Alzheimer disease. Results were compared with those in 18 healthy, matched control subjects. RESULTS: Most cortical regions were significantly atrophic in FTD and Alzheimer disease. The frontal and anterior temporal lobes were significantly more atrophic in FTD than in Alzheimer disease. The mean hemispheric-to-intracranial volume ratio in patients with FTD (56.2%) and those with Alzheimer disease (58.4%) was significantly smaller than the ratio in the control subjects (66.0%). Asymmetry of hemispheric volume was significantly larger in the FTD group than in the Alzheimer disease and control groups. CONCLUSION: Cortical atrophy in FTD is more widespread than was previously thought. Asymmetric frontal and anterior temporal atrophy is a distinctive feature of FTD and distinguishes it from Alzheimer disease. Hemispheric surface display is a useful complement to tomographic images and is useful for the evaluation of focal cortical atrophy in degenerative dementias, especially FTD.


This article has been cited by other articles:


Home page
 Arch NeurolHome page
L. L. Chao, N. Schuff, E. M. Clevenger, S. G. Mueller, H. J. Rosen, M. L. Gorno-Tempini, J. H. Kramer, B. L. Miller, and M. W. Weiner
Patterns of White Matter Atrophy in Frontotemporal Lobar Degeneration
Arch Neurol, November 1, 2007; 64(11): 1619 - 1624.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
E. Matsusue, S. Sugihara, S. Fujii, T. Kinoshita, T. Nakano, E. Ohama, and T. Ogawa
Cerebral Cortical and White Matter Lesions in Amyotrophic Lateral Sclerosis with Dementia: Correlation with MR and Pathologic Examinations
AJNR Am. J. Neuroradiol., September 1, 2007; 28(8): 1505 - 1510.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
A.-T. Du, N. Schuff, J. H. Kramer, H. J. Rosen, M. L. Gorno-Tempini, K. Rankin, B. L. Miller, and M. W. Weiner
Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia
Brain, April 1, 2007; 130(4): 1159 - 1166.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
A. T. Du, G. H. Jahng, S. Hayasaka, J. H. Kramer, H. J. Rosen, M. L. Gorno-Tempini, K. P. Rankin, B. L. Miller, M. W. Weiner, and N. Schuff
Hypoperfusion in frontotemporal dementia and Alzheimer disease by arterial spin labeling MRI.
Neurology, October 10, 2006; 67(7): 1215 - 1220.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
J. F. Norfray and J. M. Provenzale
Alzheimer's Disease: Neuropathologic Findings and Recent Advances in Imaging
Am. J. Roentgenol., January 1, 2004; 182(1): 3 - 13.
[Full Text] [PDF]

Home page
 NeurologyHome page
S. A. Thompson, K. Patterson, and J. R. Hodges
Left/right asymmetry of atrophy in semantic dementia: Behavioral-cognitive implications
Neurology, November 11, 2003; 61(9): 1196 - 1203.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
O. Kizu, K. Yamada, and T. Nishimura
Proton Chemical Shift Imaging in Pick Complex
AJNR Am. J. Neuroradiol., September 1, 2002; 23(8): 1387 - 1392.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
N. A. Thacker, A. R. Varma, D. Bathgate, S. Stivaros, J. S. Snowden, D. Neary, and A. Jackson
Dementing Disorders: Volumetric Measurement of Cerebrospinal Fluid to Distinguish Normal from Pathologic Findings—Feasibility Study
Radiology, July 1, 2002; 224(1): 278 - 285.
[Abstract] [Full Text]

Home page
 NeurologyHome page
M. Hashimoto, M. Yasuda, S. Tanimukai, M. Matsui, N. Hirono, H. Kazui, and E. Mori
Apolipoprotein E {epsilon}4 and the pattern of regional brain atrophy in Alzheimer's disease
Neurology, October 23, 2001; 57(8): 1461 - 1466.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
A T Du, N Schuff, D Amend, M P Laakso, Y Y Hsu, W J Jagust, K Yaffe, J H Kramer, B Reed, D Norman, et al.
Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
J. Neurol. Neurosurg. Psychiatry, October 1, 2001; 71(4): 441 - 447.
[Abstract] [Full Text] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
Y.-Y. Hsu, A.-T. Du, N. Schuff, and M. W. Weiner
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Dementias
J Geriatr Psychiatry Neurol, September 1, 2001; 14(3): 145 - 166.
[Abstract] [PDF]

Home page
 RadiologyHome page
Y. Ge, R. I. Grossman, J. K. Udupa, J. S. Babb, L. G. Nyul, and D. L. Kolson
Brain Atrophy in Relapsing-Remitting Multiple Sclerosis: Fractional Volumetric Analysis of Gray Matter and White Matter
Radiology, September 1, 2001; 220(3): 606 - 610.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
S. B. Prusiner
Neurodegenerative Diseases and Prions
N. Engl. J. Med., May 17, 2001; 344(20): 1516 - 1526.
[Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
H. Yamauchi, H. Fukuyama, Y. Nagahama, Y. Katsumi, T. Hayashi, C. Oyanagi, J. Konishi, and H. Shio
Comparison of the pattern of atrophy of the corpus callosum in frontotemporal dementia, progressive supranuclear palsy, and Alzheimer's disease
J. Neurol. Neurosurg. Psychiatry, November 1, 2000; 69(5): 623 - 629.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
H. Kitagaki, N. Hirono, K. Ishii, and E. Mori
Corticobasal Degeneration: Evaluation of Cortical Atrophy by Means of Hemispheric Surface Display Generated with MR Images
Radiology, July 1, 2000; 216(1): 31 - 38.
[Abstract] [Full Text]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
C Geroldi, M P Laakso, C DeCarli, A Beltramello, A Bianchetti, H Soininen, M Trabucchi, and G B Frisoni
Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study
J. Neurol. Neurosurg. Psychiatry, January 1, 2000; 68(1): 93 - 96.
[Abstract] [Full Text]

Home page
 Am. J. PsychiatryHome page
E. Mori, M. Ikeda, N. Hirono, H. Kitagaki, T. Imamura, and T. Shimomura
Amygdalar Volume and Emotional Memory in Alzheimer's Disease
Am J Psychiatry, February 1, 1999; 156(2): 216 - 222.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1998 by the Radiological Society of North America.