Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Melhem, E. R.
Right arrow Articles by Caruthers, S. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melhem, E. R.
Right arrow Articles by Caruthers, S. D.

Radiology, Vol 209, 551-555, Copyright © 1998 by Radiological Society of North America

ARTICLES

MR imaging of the hippocampus: measurement of T2 with four dual-echo techniques

ER Melhem, RE Whitehead, RJ Bert and SD Caruthers
Department of Radiology, Boston University Medical Center, Mass., USA.

PURPOSE: To assess the effect of cerebrospinal fluid (CSF) signal nulling and different magnetic resonance (MR) imaging read-out implementations on the precision of T2 measurements in the hippocampus. MATERIALS AND METHODS: Oblique coronal MR imaging was performed in 12 healthy volunteers by using four dual-echo MR sequences: conventional spin-echo (SE), fast SE, gradient-echo and SE (GRASE), and fast fluid- attenuated inversion-recovery (FLAIR) imaging. T2 measurements were obtained from T2 maps derived from regions of interest within the head of both hippocampi. T2 measurements obtained with the four MR sequences were compared, as were differences in T2 between right and left hippocampi. Interrater and test-retest consistency were determined. RESULTS: Fast FLAIR imaging provided the smallest normal range and SD of T2 measurements. Fast FLAIR and fast SE imaging provided the smallest coefficients of variation. GRASE imaging provided a lower coefficient of variation than that of conventional SE. The mean difference between left and right hippocampi was smallest at fast FLAIR imaging. CONCLUSION: Use of a CSF-nulling inversion prepulse, fast SE read-out, or GRASE read-out MR sequence helps improve the precision of the hippocampal T2 measurements in comparison with use of conventional SE imaging. T2 measurements obtained at dual-echo fast FLAIR imaging may help detect subtle hippocampal abnormalities.


This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
C. S. Georgiades, R. Itoh, X. Golay, P. C. M. van Zijl, and E. R. Melhem
MR Imaging of the Human Brain at 1.5 T: Regional Variations in Transverse Relaxation Rates in the Cerebral Cortex
AJNR Am. J. Neuroradiol., October 1, 2001; 22(9): 1732 - 1737.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
E. R. Melhem, T. F. Gotwald, R. Itoh, S. J. Zinreich, and H. W Moser
T2 Relaxation Measurements in X-linked Adrenoleukodystrophy Performed Using Dual-echo Fast Fluid-attenuated Inversion Recovery MR Imaging
AJNR Am. J. Neuroradiol., April 1, 2001; 22(4): 773 - 776.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1998 by the Radiological Society of North America.