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(Radiology. 1999;210:233-240.)
© RSNA, 1999

Technical Developments

Breast Fibroadenoma: Mapping of Pathophysiologic Features with Three-Time-Point, Contrast-enhanced MR Imaging—Pilot Study

Daphna Weinstein, MD2,1, Shalom Strano, MD3,2, Patricia Cohen, MD3, Scott Fields, MD4, J. Moshe Gomori, MD4 and Hadassa Degani, PhD2

1 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel (D.W., H.D.)
2 Department of Radiology, Kaplan Hospital, Rehovot, Israel (S.S.)
3 Departments of Pathology (P.C.)
4 Radiology (S.F., J.M.G.), Hadassah Medical Center, Jerusalem, Israel.

The capability of three-time-point, gadolinium-enhanced magnetic resonance imaging to depict vascular permeability and extracellular volume fraction of breast fibroadenoma was evaluated with histopathologic correlation. This method demonstrated an even distribution of high extracellular volume fraction and low to moderate microvascular permeability in these common breast lesions, providing a nonsurgical means of improving the accuracy of diagnosis of fibroadenoma.

Index terms: Breast neoplasms, MR, 00.121412, 00.311 • Magnetic resonance (MR), tissue characterization, 00.121412, 00.311




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