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Technical Developments |
1 Departments of Radiology (E.E.d.L., J.P.M., J.R.B., J.K.S., C.D.T.)
2 Internal Medicine (J.D.T.)
3 Surgery (T.M.D.), University of Virginia Health Sciences Center, Box 170, 1000 Lee St, Charlottesville, VA 22908
4 Magnetic Imaging Technologies, Durham, NC (P.L.B.)
5 Department of Physics, Princeton University, Princeton, NJ (G.D.C.).
Thirty-two magnetic resonance imaging examinations of the lungs were performed in 16 subjects after inhalation of 1–2 L of helium 3 gas that was laser polarized to 10%–25%. The distribution of the gas was generally uniform, with visualization of the fissures in most cases. Ventilation defects were demonstrated in smokers and in a subject with allergies. The technique has potential for evaluating small airways disease.
Index terms: Helium • Lung, MR, 60.12143 • Magnetic resonance (MR), contrast enhancement, 60.121412, 60.12143 • Magnetic resonance (MR), nuclei other than H, 60.121412, 60.12147
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