HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Horvath, L. J. Articles by Johnson, K. M. Search for Related Content PubMed PubMed Citation Articles by Horvath, L. J. Articles by Johnson, K. M.

Total-Body Echo-planar MR Imaging in the Staging of Breast Cancer: Comparison with Conventional Methods—Early Experience¹

¹ From the Departments of Diagnostic Radiology (L.J.H., S.M., K.M.J.) and Internal Medicine (B.A.B.), Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510. From the 1996 RSNA scientific assembly. Received March 16, 1998; revision requested May 12; revision received August 4; accepted October 13. Address reprint requests to L.J.H.

PURPOSE: To test breast cancer staging with total-body echo-planar magnetic resonance (MR) imaging.

MATERIALS AND METHODS: Nineteen patients with newly diagnosed breast cancer were imaged by using a 1.5-T echo-planar MR system. By using a table sweep method, 180 contiguous axial images were obtained from the cranial vertex through the feet with T2-weighted spin-echo and inversion-recovery sequences. Results were compared with those of conventional imaging. Therapeutic decisions based on echo-planar MR imaging and conventional imaging results were compared. Diagnostic truth was determined by means of tissue diagnosis, further imaging findings, and follow-up findings (median, 18 months).

RESULTS: Staging with total-body echo-planar MR imaging was correct in 18 patients (95%)—eight with metastases and 10 without—while staging with conventional imaging was correct in 15 patients (79%). In one patient, both echo-planar MR imaging and conventional imaging findings incorrectly indicated probable metastases. In one patient thought to have bone metastases at conventional imaging, echo-planar MR imaging findings were normal, which was correct. Two patients with stage IV disease were not suspected to have disease at conventional imaging: One had liver involvement and the other had skeletal metastases. The therapeutic decisions in these two patients were altered by the echo-planar MR imaging results.

CONCLUSION: Total-body echo-planar MR imaging was at least as accurate as conventional imaging for staging newly diagnosed breast cancer and was faster, simpler, and completely noninvasive.

Index terms: Bone neoplasms, radionuclide studies, 30.12172, 30.33, 40.12172, 40.33 • Breast neoplasms, 00.32, 00.33 • Neoplasms, CT, _**.1211, .30² • Neoplasms, MR, _**.121411, _**.121413, _**.30 • Neoplasms, radionuclide studies, _**.12172, _**.30 • Neoplasms, staging, _**.30

This article has been cited by other articles:

				K. Brauck, M. O. Zenge, F. M. Vogt, H. H. Quick, F. Stock, T. Trarbach, M. E. Ladd, and J. Barkhausen Feasibility of Whole-Body MR with T2- and T1-weighted Real-time Steady-State Free Precession Sequences during Continuous Table Movement to Depict Metastases Radiology, March 1, 2008; 246(3): 910 - 916. [Abstract] [Full Text] [PDF]

				T. C. Lauenstein, S. C. Goehde, C. U. Herborn, M. Goyen, C. Oberhoff, J. F. Debatin, S. G. Ruehm, and J. Barkhausen Whole-Body MR Imaging: Evaluation of Patients for Metastases Radiology, October 1, 2004; 233(1): 139 - 148. [Abstract] [Full Text] [PDF]

				A. Mazumdar, M. J. Siegel, V. Narra, and L. Luchtman-Jones Whole-Body Fast Inversion Recovery MR Imaging of Small Cell Neoplasms in Pediatric Patients: A Pilot Study Am. J. Roentgenol., November 1, 2002; 179(5): 1261 - 1266. [Abstract] [Full Text] [PDF]

				T. C. Lauenstein, S. C. Goehde, C. U. Herborn, W. Treder, S. G. Ruehm, J. F. Debatin, and J. Barkhausen Three-Dimensional Volumetric Interpolated Breath-Hold MR Imaging for Whole-Body Tumor Staging in Less Than 15 Minutes: A Feasibility Study Am. J. Roentgenol., August 1, 2002; 179(2): 445 - 449. [Abstract] [Full Text] [PDF]

				M. J. Siegel, H. Ishwaran, B. D. Fletcher, J. S. Meyer, F. A. Hoffer, D. Jaramillo, R. J. Hernandez, S. E. Roubal, B. A. Siegel, D. J. Caudry, et al. Staging of Neuroblastoma at Imaging: Report of the Radiology Diagnostic Oncology Group Radiology, April 1, 2002; 223(1): 168 - 175. [Abstract] [Full Text] [PDF]

				H. Schirrmeister, G. Glatting, J. Hetzel, K. Nussle, C. Arslandemir, A. K. Buck, K. Dziuk, A. Gabelmann, S. N. Reske, and M. Hetzel Prospective Evaluation of the Clinical Value of Planar Bone Scans, SPECT, and 18F-Labeled NaF PET in Newly Diagnosed Lung Cancer J. Nucl. Med., December 1, 2001; 42(12): 1800 - 1804. [Abstract] [Full Text] [PDF]

				H. E. Daldrup-Link, C. Franzius, T. M. Link, D. Laukamp, J. Sciuk, H. Jurgens, O. Schober, and E. J. Rummeny Whole-Body MR Imaging for Detection of Bone Metastases in Children and Young Adults: Comparison with Skeletal Scintigraphy and FDG PET Am. J. Roentgenol., July 1, 2001; 177(1): 229 - 236. [Abstract] [Full Text] [PDF]

				J. Barkhausen, H. H. Quick, T. Lauenstein, M. Goyen, S. G. Ruehm, G. Laub, J. F. Debatin, and M. E. Ladd Whole-Body MR Imaging in 30 Seconds with Real-Time True FISP and a Continuously Rolling Table Platform: Feasibility Study Radiology, July 1, 2001; 220(1): 252 - 256. [Abstract] [Full Text] [PDF]

				T. Taoka, N. A. Mayr, H. J. Lee, W. T. C. Yuh, T. M. Simonson, K. Rezai, and K. S. Berbaum Factors Influencing Visualization of Vertebral Metastases on MR Imaging Versus Bone Scintigraphy Am. J. Roentgenol., June 1, 2001; 176(6): 1525 - 1530. [Abstract] [Full Text] [PDF]