| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Thoracic Imaging |
1 From the Dept of Radiology, Osaka University Medical School, Japan (T.J., H.N.); Dept of Radiology, Vancouver Hospital and Health Sciences Centre and University of British Columbia, 855 W 12th Ave, Vancouver V5Z 1M9, Canada (T.J., N.L.M.); Dept of Radiology, Kyoto University Medical School, Japan (H.I.); First Dept of Internal Medicine, Kumamoto University School of Medicine, Japan (K.I.); Dept of Radiology, Ehime University Medical School, Japan (J.I.); Dept of Radiology, National Kinki Chuo Hospital for Chest Diseases, Osaka, Japan (M.A.); and Dept of Pathology, Izumisano Municipal Hospital, Osaka (T.N.). From the 1996 RSNA scientific assembly. Received Apr 2, 1998; revision requested Jun 29; final revision received Sep 8; accepted Oct 26. Address reprint requests to N.L.M.
PURPOSE: To determine the spectrum of diseases associated with a fine reticular pattern superimposed on areas of ground-glass opacity (ie, "crazy-paving" appearance) at thin-section computed tomography (CT) and to determine the underlying pathologic features.
MATERIALS AND METHODS: In the in vivo study, the cases of 46 patients (21 male, 25 female; age range, 13–82 years) were retrospectively reviewed, with special attention paid to the size and extent of the reticular network. In the in vitro study, the thin-section CT findings in 20 inflated and fixed lungs were precisely correlated with the gross appearance, contact radiograph findings, stereomicroscopic views, and histologic findings.
RESULTS: In the in vivo study, 15 different diseases were identified, including alveolar proteinosis, adult respiratory distress syndrome, acute interstitial pneumonia, diffuse alveolar damage superimposed on usual interstitial pneumonia, and drug-induced pneumonitis. In the in vitro study, the fine networks at pathologic analysis were due to an alveolar filling process (n = 10), an interstitial fibrotic process (n = 7), or a combination of interstitial and intraalveolar processes (n = 3). Twelve (60%) cases did not have thickening of the interlobular septa within the areas of the crazy-paving appearance.
CONCLUSION: The crazy-paving appearance is a nonspecific finding seen in a variety of interstitial and airspace lung diseases.
Index terms: Computed tomography (CT), comparative studies, 60.126, 60.1292, 68.11, 68.12118 • Computed tomography (CT), thin-section, 68.12118 • Lung, CT, 60.12118 • Lung, diseases, 60.2061, 60.2075, 60.213, 60.2173, 60.23, 60.4123, 60.413, 60.47, 60.632, 60.71 • Lung, infection, 60.20 • Pneumonia, acute interstitial, 60.213 • Proteinosis, pulmonary alveolar, 60.791 • Respiratory distress syndrome, adult, 60.413
This article has been cited by other articles:
|
|
 |
|
  A. A. Frazier, T. J. Franks, E. O. Cooke, T.-L. H. Mohammed, R. D. Pugatch, and J. R. Galvin From the Archives of the AFIP: Pulmonary Alveolar Proteinosis RadioGraphics, May 1, 2008; 28(3): 883 - 899. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. H. Lee The Crazy-paving Sign Radiology, June 1, 2007; 243(3): 905 - 906. [Full Text] [PDF]
|
|
|
|
 |
|
 M. E. Dexter, G. P. Cosgrove, and I. S. Douglas Managing a Rare Condition Presenting With Intractable Hypoxemic Respiratory Failure Chest, January 1, 2007; 131(1): 320 - 327. [Full Text] [PDF]
|
|
|
|
 |
|
 O C Ioachimescu and M S Kavuru Pulmonary alveolar proteinosis Chronic Respiratory Disease, July 1, 2006; 3(3): 149 - 159. [Abstract] [PDF]
|
|
|
|
|
|
W. R. Webb Thin-Section CT of the Secondary Pulmonary Lobule: Anatomy and the Image--The 2004 Fleischner Lecture Radiology, May 1, 2006; 239(2): 322 - 338. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Nambu, A. Saito, T. Araki, K. Ozawa, Y. Hiejima, M. Akao, Z. Ohki, and H. Yamaguchi Chlamydia Pneumoniae: Comparison with Findings of Mycoplasma Pneumoniae and Streptococcus Pneumoniae at Thin-Section CT Radiology, December 1, 2005; 238(1): 330 - 338. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. J. O'Donnell, R. L. Kradin, A. E. Evins, and C. Wittram Case 39-2004 - A 52-Year-Old Woman with Recurrent Episodes of Atypical Pneumonia N. Engl. J. Med., December 23, 2004; 351(26): 2741 - 2749. [Full Text] [PDF]
|
|
|
|
 |
|
 E L Gasparetto, P Tazoniero, D L Escuissato, E Marchiori, R L Frare e Silva, and D Sakamoto Pulmonary alveolar microlithiasis presenting with crazy-paving pattern on high resolution CT Br. J. Radiol., November 1, 2004; 77(923): 974 - 976. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. C. Ooi, P. L. Khong, N. L. Muller, W. C. Yiu, L. J. Zhou, J. C. M. Ho, B. Lam, S. Nicolaou, and K. W. T. Tsang Severe Acute Respiratory Syndrome: Temporal Lung Changes at Thin-Section CT in 30 Patients Radiology, March 1, 2004; 230(3): 836 - 844. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. Joynt, G. E. Antonio, P. Lam, K. T. Wong, T. Li, C. D. Gomersall, and A. T. Ahuja Late-Stage Adult Respiratory Distress Syndrome Caused by Severe Acute Respiratory Syndrome: Abnormal Findings at Thin-Section CT Radiology, February 1, 2004; 230(2): 339 - 346. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. C. Trapnell, J. A. Whitsett, and K. Nakata Pulmonary Alveolar Proteinosis N. Engl. J. Med., December 25, 2003; 349(26): 2527 - 2539. [Full Text] [PDF]
|
|
|
|
|
|
K. T. Wong, G. E. Antonio, D. S. C. Hui, N. Lee, E. H. Y. Yuen, A. Wu, C. B. Leung, T. H. Rainer, P. Cameron, S. S. C. Chung, et al. Thin-Section CT of Severe Acute Respiratory Syndrome: Evaluation of 73 Patients Exposed to or with the Disease Radiology, August 1, 2003; 228(2): 395 - 400. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. E. Antonio, K. T. Wong, D. S. C. Hui, N. Lee, E. H. Y. Yuen, A. Wu, S. S. C. Chung, J. J. Y. Sung, and A. T. Ahuja Imaging of Severe Acute Respiratory Syndrome in Hong Kong Am. J. Roentgenol., July 1, 2003; 181(1): 11 - 17. [Full Text] [PDF]
|
|
|
|
 |
|
 C. Raynaud, B. Crestani, M. Grossin, M. Piperaud, M-C. Dombret, and M. Aubier Lung infiltrate in a male with a bronchopleural fistula Eur. Respir. J., June 1, 2003; 21(6): 1078 - 1080. [Full Text] [PDF]
|
|
|
|
|
|
T. Johkoh, N. L. Muller, T. V. Colby, K. Ichikado, H. Taniguchi, Y. Kondoh, K. Fujimoto, M. Kinoshita, H. Arakawa, H. Yamada, et al. Nonspecific Interstitial Pneumonia: Correlation between Thin-Section CT Findings and Pathologic Subgroups in 55 Patients Radiology, October 1, 2002; 225(1): 199 - 204. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Akira, H. Ishikawa, and S. Yamamoto Drug-induced Pneumonitis: Thin-Section CT Findings in 60 Patients Radiology, September 1, 2002; 224(3): 852 - 860. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. F. Seymour and J. J. Presneill Pulmonary Alveolar Proteinosis: Progress in the First 44 Years Am. J. Respir. Crit. Care Med., July 15, 2002; 166(2): 215 - 235. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Holbert, P. Costello, W. Li, R. M. Hoffman, and R. M. Rogers CT Features of Pulmonary Alveolar Proteinosis Am. J. Roentgenol., May 1, 2001; 176(5): 1287 - 1294. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E Coche, B Weynand, P Noirhomme, and T Pieters Non-specific interstitial pneumonia showing a ""crazy paving"" pattern on high resolution CT Br. J. Radiol., February 1, 2001; 74(878): 189 - 191. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Akira, G. Inoue, S. Yamamoto, and M. Sakatani Non-specific interstitial pneumonia: findings on sequential CT scans of nine patients Thorax, October 1, 2000; 55(10): 854 - 859. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| RADIOLOGY | RADIOGRAPHICS | RSNA JOURNALS ONLINE |
