Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jelinek, J. S.
Right arrow Articles by Snearly, W. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jelinek, J. S.
Right arrow Articles by Snearly, W. N.
(Radiology. 1999;211:241-247.)
© RSNA, 1999

Musculoskeletal Imaging

Muscle Infarction in Patients with Diabetes Mellitus: MR Imaging Findings1

James S. Jelinek, MD, Mark D. Murphey, MD, Albert J. Aboulafia, MD, Robert G. Dussault, MD, Phoebe A. Kaplan, MD and William N. Snearly, MD 1

1 From the Depts of Radiology and Orthopedic Oncology, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010 (J.S.J.); Dept of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC (J.S.J., M.D.M.); Dept of Radiology, University of Maryland School of Medicine, Baltimore (M.D.M.); Depts of Radiology and Nuclear Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md (M.D.M.); Section of Orthopedics, Emory University School of Medicine, Atlanta, Ga (A.J.A.); and Dept of Radiology, University of Virginia, Health Sciences Center, Charlottesville (R.G.D., P.A.K., W.N.S.). From the 1997 RSNA scientific assembly. Received Nov 18, 1997; revision requested Feb 5, 1998; final revision received Aug 20; accepted Nov 6. Address reprint requests to J.S.J.

PURPOSE: To describe the magnetic resonance (MR) imaging findings in diabetic patients with muscle infarction and to describe commonly associated clinical features.

MATERIALS AND METHODS: The MR imaging studies of 21 patients with diabetic muscle infarction were reviewed retrospectively. Of the 21 patients, 12 were women, and nine were men; the mean age was 48 years (range, 30–77 years).

RESULTS: Eight patients had bilateral lower-extremity involvement; six had involvement confined to the right lower extremity and seven to the left. The thigh was involved in 17 patients (81%). One or more of the musculi vastus, the most frequently affected muscle group, were affected in 16 patients (76%). Four patients (19%) had isolated calf involvement. MR imaging studies showed diffuse enlargement of involved muscle groups and partial loss of normal fatty intermuscular septa. MR imaging also allowed identification of areas of subfascial fluid in 16 patients (76%) and subcutaneous edema in 19 patients (90%). MR imaging showed involved muscle groups best with T2-weighted, inversion-recovery, and gadolinium-enhanced sequences, where the infarcted muscles appeared diffusely hyperintense compared with adjacent muscles. Comparison of T2-weighted and gadolinium-enhanced MR images of nine patients showed enlarged, enhancing muscles in all patients and small, focal, rim-enhancing fluid collections in six of nine patients (66%).

CONCLUSION: Diabetic muscle infarction is suggested in diabetic patients with sudden onset of severe pain in the thigh or calf muscles who have MR imaging findings of diffuse edema and swelling of multiple thigh and calf muscles (often in more than one compartment).

Index terms: Diabetes mellitus, complications, 44.44, 44.833, 45.44, 45.833 • Muscles, infarction, 44.44, 44.833, 45.44, 45.833 • Muscles, MR, 44.1214, 44.121411, 44.121413, 44.12143, 45.1214, 45.121411, 45.121413, 45.12143




This article has been cited by other articles:


Home page
 BMJHome page
M. S Parmar
Diabetic muscle infarction
BMJ, June 19, 2009; 338(jun19_1): b2271 - b2271.
[Full Text]

Home page
 RadiologyHome page
A. M. Heemskerk, G. J. Strijkers, M. R. Drost, G. S. van Bochove, and K. Nicolay
Skeletal Muscle Degeneration and Regeneration after Femoral Artery Ligation in Mice: Monitoring with Diffusion MR Imaging
Radiology, May 1, 2007; 243(2): 413 - 421.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
K. L. Lentine and S. S. Guest
Diabetic muscle infarction in end-stage renal disease
Nephrol. Dial. Transplant., March 1, 2004; 19(3): 664 - 669.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
J. Q. Ly, E. K. Yi, and D. P. Beall
Diabetic Muscle Infarction
Am. J. Roentgenol., November 1, 2003; 181(5): 1216 - 1216.
[Full Text] [PDF]

Home page
 Diabetes CareHome page
A. J. Trujillo-Santos
Diabetic Muscle Infarction: An underdiagnosed complication of long-standing diabetes
Diabetes Care, January 1, 2003; 26(1): 211 - 215.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
K. M. Chow, C. C. Szeto, T. Y.-h. Wong, F. K.-t. Leung, A. Cheuk, and P. K.-t. Li
Diabetic Muscle Infarction: Myocardial infarct equivalent
Diabetes Care, October 1, 2002; 25(10): 1895 - 1895.
[Full Text]

Home page
 Ann Rheum DisHome page
L Silberstein, K E Britton, F P Marsh, M J Raftery, and D D'Cruz
An unexpected cause of muscle pain in diabetes
Ann Rheum Dis, April 1, 2001; 60(4): 310 - 312.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
L. O. Delaney-Sathy, D. P. Fessell, J. A. Jacobson, and C. W. Hayes
Sonography of Diabetic Muscle Infarction with MR Imaging, CT, and Pathologic Correlation
Am. J. Roentgenol., January 1, 2000; 174(1): 165 - 169.
[Abstract] [Full Text] [PDF]