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Gastrointestinal Imaging |
1 From the Department of Radiology, Osaka University Medical School, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan. From the 1997 RSNA scientific assembly. Received June 17, 1998; revision requested July 30; revision received September 22; accepted December 15. Address reprint requests to T.K. (e-mail: kim@radiol.med.osakau.ac.jp).
PURPOSE: To assess the effects of the intravenous injection rate and dose of contrast material on pancreatic computed tomography (CT).
MATERIALS AND METHODS: A total of 126 patients were divided at random into four groups with different injection rates and doses. Groups 1 and 2 underwent injection of 2 mL per kilogram of body weight of 300 mg of iodine per milliliter of contrast material, and groups 3 and 4 underwent injection of 1.5 mL/kg. The injection rate was 5 mL/sec for groups 1 and 3 and 3 mL/sec for groups 2 and 4. Single-level serial CT scanning was performed at the level of the pancreatic head, and the pancreatic enhancement value was calculated.
RESULTS: The maximum pancreatic enhancement value was 99 HU ± 18 (mean ± SD) for group 1, 90 HU ± 18 for group 2, 86 HU ± 15 for group 3, and 74 HU ± 13 for group 4. There were significant differences in the maximum pancreatic enhancement value between groups 1 and 2 (P = .045), between groups 3 and 4 (P = .001), between groups 1 and 3 (P = .016), and between groups 2 and 4 (P = .001).
CONCLUSION: Both a higher dose and a faster injection rate increased the maximum pancreatic enhancement value.
Index terms: Computed tomography (CT), contrast enhancement, 770.12112, 770.12119 • Pancreas, CT, 770.12112, 770.12119 • Pancreas, neoplasms, 770.32
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