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Thoracic Imaging |
1 From the Department of Radiology, Vancouver Hospital and Health Sciences Center and University of British Columbia, 855 W 12th Ave, Vancouver, British Columbia, Canada V5Z 1M9 (T.J., N.L.M.); the Department of Radiology, Osaka University Medical School, Japan (T.J., O.H., H.N.); the Department of Radiology, Mayo Clinic, Rochester, Minn (H.A.P., T.E.H.); the First Department of Internal Medicine, Kumamoto University School of Medicine, Japan (K.I.); and the Department of Radiology, National Kinki Chuo Hospital for Chest Disease, Osaka, Japan (M.A.). Received March 25, 1998; revision requested June 18; final revision received October 23; accepted February 12, 1999. Address reprint requests to N.L.M.
PURPOSE: To assess the thin-section computed tomographic (CT) findings of lymphocytic interstitial pneumonia.
MATERIALS AND METHODS: The study included 22 patients (five men, 17 women; age range, 2483 years; mean age, 50 years) with biopsy-proved lymphocytic interstitial pneumonia. The CT scans were obtained by using 13-mm collimation and reconstructed by using a high-spatial-frequency algorithm.
RESULTS: The predominant abnormalities consisted of areas of ground-glass attenuation and poorly defined centrilobular nodules present in all 22 patients and subpleural small nodules seen in 19 patients. Other common findings included thickening of bronchovascular bundles (n = 19), interlobular septal thickening (n = 18), cystic airspaces (n = 15), and lymph node enlargement (n = 15). Less common findings included large nodules, emphysema, airspace consolidation, bronchiectasis, architectural distortion, honeycombing, and pleural thickening.
CONCLUSION: Lymphocytic interstitial pneumonia is characterized by the presence of ground-glass attenuation, poorly defined centrilobular nodules, and thickening of the interstitium along the lymphatic vessels. Lymph node enlargement is more common than previously recognized; it was seen in 68% of patients.
Index terms: Acquired immunodeficiency syndrome (AIDS), 60.206, 60.2068, 60.2518 Castleman disease, 60.314, 60.391 Eye, diseases, 22.696 Lung, CT, 60.12112, 60.12118 Pneumonitis, lymphocytic interstitial, 60.795 Sjögren syndrome, 22.696, 60.795
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