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Vascular and Interventional Radiology |
1 From the Departments of Radiology, University of Texas–Houston Health Science Center Medical School, 6431 Fannin St, Houston, TX 77030 (L.K.W.); the M.D. Anderson Cancer Center, Houston, Tex (M.D.M.); the University of Michigan, Ann Arbor (M.V.M.); and the University of Kansas, Kansas City (E.L.S.). Received December 21, 1998; revision requested March 2, 1999; revision received April 14; accepted June 10. Address reprint requests to L.K.W. (e-mail: Louis.K.Wagner@uth.tmc.edu).
Some patients with certain preexisting health conditions may be at elevated risk for unusually intense radiation-induced skin reactions and late tissue damage from high-dose interventional procedures. The authors present a case report of a patient with mixed connective tissue disease and non–insulin-dependent diabetes mellitus who developed an unusual complication after placement of a transjugular intrahepatic portosystemic shunt. On the basis of a review of the literature, the following experiences may help identify patients at increased risk: previous high-dose procedures, connective tissue disease, diabetes mellitus, and homozygosity for ataxia telangiectasia.
Index terms: Ataxia telangiectasia • Connective tissue, diseases, **3.61, **.47 • Diabetes Mellitus • Interventional procedures, complications • Skin, effects of irradiation on, 30.47, 40.47
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