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Sinus Histiocytosis (Rosai-Dorfman Disease) of the Suprasellar Region: MR Imaging Findings-A Case Report¹

¹ From the Departments of Radiology (R.J.W., M.H.L.) and Pathology (J.W.M.), University of Virginia, Charlottesville, Va. Received December 23, 1998; revision requested February 2, 1999; revision received February 16; accepted June 8. Address reprint requests to R.J.W., Department of Radiology, Emory University Hospital, 1364 Clifton Rd, NE, Atlanta, GA 30322. (e-mail: rjwoodcock@hotmail.com).

Sinus histiocytosis with massive lymphadenopathy (SHML) is an uncommon disorder that typically manifests as systemic symptoms and lymphadenopathy. Extranodal, intracranial disease is uncommon. The authors report on a 15-year-old adolescent girl who had a suprasellar mass at magnetic resonance imaging. Biopsy results demonstrated lymphophagocytosis consistent with a diagnosis of SHML. The clinical, radiologic, and histologic aspects of the disease are discussed.

Index terms: Histiocytosis, 145.66 • Pituitary, abnormalities, 145.66 • Pituitary, MR, 145.121411 • Sella turcica, 122.66

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