HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Freed, K. S. Articles by Nelson, R. C. Search for Related Content PubMed PubMed Citation Articles by Freed, K. S. Articles by Nelson, R. C.

Pelvic CT Morphometry in Down Syndrome: Implications for Prenatal US Evaluation-Preliminary Results¹

¹ From the Department of Radiology, Duke University Medical Center, Box 3808, Erwin Rd, Durham, NC 27710. Received December 4, 1998; revision requested February 15, 1999; revision received April 15; accepted June 10. Address reprint requests to K.S.F. (e-mail: freed005@mc.duke.edu).

PURPOSE: To characterize pelvic morphometric differences in patients with and those without Down syndrome by using computed tomography (CT) and to determine useful indexes for ultrasonographic (US) evaluation.

MATERIALS AND METHODS: Pelvic CT scans in seven patients with Down syndrome and in 27 patients without Down syndrome were reviewed. Iliac angle, iliac length, sacroiliac joint angle, and anterior iliac wing separation were measured at superior, middle, and inferior transverse sacral levels. The effects of chromosomal status and transverse level were evaluated statistically.

RESULTS: Significant differences were found for mean iliac angle (P < .007) and length (P < .005) between patients without Down syndrome (angle, 75°; length, 8.4 cm) and those with Down syndrome (angle, 82°; length, 7.5 cm). Depending on the level of measurement, variations in iliac angle between patients without and those with Down syndrome were as much as 13° and 15°, respectively, and variations in length were as much as 1.6 cm and 0.9 cm, respectively. The greatest differences were at the middle sacral level. Sacroiliac joint angle and the anterior iliac wing separation were not different between groups.

CONCLUSION: Patients with Down syndrome had a larger mean iliac angle and a shorter mean iliac length. The most pronounced differences were at the middle sacral level, which suggests that this may be the optimal level for measuring these parameters at prenatal US.

Index terms: Children, skeletal system, 44.1841 • Down syndrome, 44.1841 • Infants, skeletal system, 44.1841 • Pelvis, CT, 44.1211

This article has been cited by other articles:

				M. A. Kliewer, B. S. Hertzberg, K. S. Freed, P. J. McNally, and D. M. DeLong The Anterior Iliac Separation: Alternative Index for Pelvic Morphometry in Fetuses with Down Syndrome Am. J. Roentgenol., April 1, 2001; 176(4): 1003 - 1007. [Abstract] [Full Text] [PDF]