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(Radiology. 2000;214:223-226.)
© RSNA, 2000


Neuroradiology

Spontaneous Involution of Pilocytic Astrocytoma in a Patient without Neurofibromatosis Type 1: Case Report1

Massimo Gallucci, MD, Alessia Catalucci, MD, Bernd W. Scheithauer, MD and Glenn S. Forbes, MD

1 From the Department of Radiology, University of L'Aquila, Nuovo S. Salvatore Hospital, Coppito, 67100 L'Aquila, Italy (M.G., A.C.), and the Departments of Laboratory Medicine and Pathology (B.W.S.) and Radiology (G.S.F.), Mayo Clinic, Rochester, Minn. Received April 21, 1998; revision requested July 2; final revision received March 10, 1999; accepted June 15. Address reprint requests to M.G. (e-mail: nradaq@tin.it).

Serial magnetic resonance imaging findings are described in a patient with a sporadically occurring pilocytic astrocytoma that underwent spontaneous regression over 6 years. To the authors' knowledge, this is the first report in which spontaneous involution of a pilocytic astrocytoma not associated with neurofibromatosis type 1 has been described. A literature review regarding sporadic and syndrome-associated pilocytic astrocytoma was undertaken, with particular reference to treatment and natural history.

Index terms: Astrocytoma, 15.313 • Brain, MR, 15.121411, 15.12143 • Neurofibromatosis, 15.313




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