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(Radiology. 2000;215:910-916.)
© RSNA, 2000

Technical Developments

Normal Lumbar Vertebrae: Anatomic, Age, and Sex Variance in Subjects at Proton MR Spectroscopy-Initial Experience1

Dieter Schellinger, MD, Chin Shoou Lin, PhD, Djamil Fertikh, MD, Jacob S. Lee, MD, MS, William C. Lauerman, MD, Fraser Henderson, MD and Bolivia Davis, MD

1 From the Departments of Radiology (D.S., C.S.L., D.F., J.S.L., B.D.), Orthopedic Surgery (W.C.L.), and Neurosurgery (F.H.), Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007. From the 1998 RSNA scientific assembly. Received January 25, 1999; revision requested March 24; final revision received September 27; accepted October 20. Address correspondence to D.S. (e-mail: dschell37@aol.com).

Fifty-seven subjects underwent proton magnetic resonance (MR) spectroscopy of the second lumbar vertebra to evaluate single-voxel and multivoxel techniques. Measurements included lipid-to-water ratios, lipid fractions, and line width. These data provide information about vertebral fat content. There was an age-dependent linear increase in fat content and sex dependence. A higher fat concentration was found in men. The observed spectra provide a basis for future study to determine clinical utility of vertebral proton MR spectroscopy.

Index terms: Bone marrow, MR, 30.12145 • Magnetic resonance (MR), chemical shift, 30.12145 • Magnetic resonance (MR), spectroscopy, 30.12145 • Spine, MR, 30.12145




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