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Gastrointestinal Imaging |
1 From the Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center (N.A.A., A.J.D.), and the Pulmonary–Critical Care Medical Branch, National Heart, Lung, and Blood Institute (J.A.K., S.C.C., J.M.), National Institutes of Health, Bldg 10, Rm 1C-660, 10 Center Dr MSC 1182, Bethesda, MD 20892-1182. Received May 18, 1999; revision requested October 1; final revision received November 1; accepted November 10. Address correspondence to N.A.A. (e-mail: navila@nih.gov).
PURPOSE: To describe the abdominal computed tomographic (CT) and ultrasonographic (US) findings in patients with thoracic lymphangioleiomyomatosis (LAM) and to relate the prevalence of the findings to the severity of pulmonary disease.
MATERIALS AND METHODS: Eighty patients with LAM underwent chest and abdominopelvic CT and abdominopelvic US. The images were reviewed prospectively by one radiologist, and the abdominal findings were recorded and correlated with the severity of pulmonary disease at thin-section CT.
RESULTS: Sixty-one (76%) of 80 patients had positive abdominal findings. The most common abdominal findings included renal angiomyolipoma (AML) in 43 patients (54%), enlarged abdominal lymph nodes in 31 (39%), and lymphangiomyoma in 13 (16%). Less common findings included ascites in eight (10%), dilatation of the thoracic duct in seven (9%), and hepatic AML in three (4%). A significant correlation (P = .02) was observed between enlarged abdominal lymph nodes and increased severity of lung disease.
CONCLUSION: There are characteristic abdominal findings in patients with LAM that, in conjunction with the classic thin-section CT finding of pulmonary cysts, are useful in establishing this diagnosis.
Index terms: Angiomyolipoma, 81.3141 • Kidney neoplasms, CT, 81.12111, 81.12112, 81.3141, 81.3199 • Kidney neoplasms, US, 81.1298, 81.3141, 81.3199 • Liver neoplasms, 761.3141 • Lung, CT, 60.12111, 60.12112, 60.319, 60.829 • Lung, diseases, 60.799 • Lymphangiomyomatosis, 993.829 • Lymphatic system, CT, 99.12911, 99.12912, 99.12918 • Lymphatic system, US, 99.12983, 99.12984
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