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(Radiology. 2000;216:597-602.)
© RSNA, 2000


Technical Developments

Left Ventricular Mass and Volume: Fast Calculation with Guide-Point Modeling on MR Images1

Alistair A. Young, PhD, Brett R. Cowan, BE, MBChB, Steven F. Thrupp, MA, Warren J. Hedley, ME and Louis J. Dell’Italia, MD

1 From the Departments of Anatomy with Radiology (A.A.Y.), Medicine (B.R.C., S.F.T.), and Engineering Science (W.J.H.), University of Auckland, 85 Park Road, Auckland, New Zealand; and the Department of Medicine, University of Alabama at Birmingham, Ala (L.J.D.). Received August 13, 1999; revision requested October 5; revision received November 12; accepted December 20. Supported in part by the Auckland Medical Research Foundation and the Health Research Council of New Zealand. Address correspondence to A.A.Y. (e-mail: a.young@auckland.ac.nz).

The authors describe a fast method for calculating left ventricle (LV) mass and volumes from multiplanar magnetic resonance (MR) images. Mathematic models were fitted to a small number of user-selected guide points in 15 healthy volunteers, 13 patients after myocardial infarction, and a canine model of mitral regurgitation in eight dogs. Errors between model and manual contours were small (LV mass, 1.8 g ± 4.9 [mean ± SD]; end-diastolic volume, 2.2 mL ± 4.6; end-systolic volume, 2.3 mL ± 3.8). Estimates of global function could be obtained in 6 minutes, a time saving of 5–10 times over estimates with manual contouring.

Index terms: Heart, volume, 51.92 • Magnetic resonance (MR), phase imaging, 51.12144 • Magnetic resonance (MR), rapid imaging, 51.121416 • Magnetic resonance (MR), volume measurement, 51.12144




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